PDB entry 3d5u

View 3d5u on RCSB PDB site
Description: Crystal structure of a wildtype Polo-like kinase 1 (Plk1) catalytic domain.
Class: transferase
Keywords: Polo-like kinase 1, Plk1, catalytic domain, small-molecule inhibitor, Kinase, TRANSFERASE
Deposited on 2008-05-17, released 2008-08-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.231
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Polo-like kinase 1
    Species: Danio rerio [TaxId:7955]
    Gene: PLK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3d5ua_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3d5uA (A:)
    gplgsmsaaiakpsakpsahvdpksaplkeipdvlvdprtmkrymrgrflgkggfakcye
    itdmdtkevfagkvvpksmllkphqkekmsteiaihksldnphvvgfhgffedddfvyvv
    leicrrrsllelhkrrkavtepearyfmrqtiqgvqylhnnrvihrdlklgnlflnddmd
    vkigdfglatkiefdgerkktlcgtpnyiapevlckkghsfevdiwslgcilytllvgkp
    pfetsclketyirikkneysvprhinpvasalirrmlhadptlrpsvaelltdefftsgy
    apmrlptscltvpprfs
    

    Sequence, based on observed residues (ATOM records): (download)
    >3d5uA (A:)
    lkeipdvlvdprtmkrymrgrflgkggfakcyeitdmdtkevfagkvvpksmllkphqke
    kmsteiaihksldnphvvgfhgffedddfvyvvleicrrrsllelhkrrkavtepearyf
    mrqtiqgvqylhnnrvihrdlklgnlflnddmdvkigdfglatkiefdgerkktlcgtpn
    yiapevlckkghsfevdiwslgcilytllvgkppfetsclketyirikkneysvprhinp
    vasalirrmlhadptlrpsvaelltdefftsgyapmrlptscltvppr