PDB entry 3d5u
View 3d5u on RCSB PDB site
Description: Crystal structure of a wildtype Polo-like kinase 1 (Plk1) catalytic domain.
Class: transferase
Keywords: Polo-like kinase 1, Plk1, catalytic domain, small-molecule inhibitor, Kinase, TRANSFERASE
Deposited on
2008-05-17, released
2008-08-26
The last revision prior to the SCOPe 2.06 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.231
AEROSPACI score: 0.26
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Polo-like kinase 1
Species: Danio rerio [TaxId:7955]
Gene: PLK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3d5ua_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3d5uA (A:)
gplgsmsaaiakpsakpsahvdpksaplkeipdvlvdprtmkrymrgrflgkggfakcye
itdmdtkevfagkvvpksmllkphqkekmsteiaihksldnphvvgfhgffedddfvyvv
leicrrrsllelhkrrkavtepearyfmrqtiqgvqylhnnrvihrdlklgnlflnddmd
vkigdfglatkiefdgerkktlcgtpnyiapevlckkghsfevdiwslgcilytllvgkp
pfetsclketyirikkneysvprhinpvasalirrmlhadptlrpsvaelltdefftsgy
apmrlptscltvpprfs
Sequence, based on observed residues (ATOM records): (download)
>3d5uA (A:)
lkeipdvlvdprtmkrymrgrflgkggfakcyeitdmdtkevfagkvvpksmllkphqke
kmsteiaihksldnphvvgfhgffedddfvyvvleicrrrsllelhkrrkavtepearyf
mrqtiqgvqylhnnrvihrdlklgnlflnddmdvkigdfglatkiefdgerkktlcgtpn
yiapevlckkghsfevdiwslgcilytllvgkppfetsclketyirikkneysvprhinp
vasalirrmlhadptlrpsvaelltdefftsgyapmrlptscltvppr