PDB entry 3d3x

View 3d3x on RCSB PDB site
Description: Crystal structure of botulinum neurotoxin serotype E catalytic domain in complex with SNAP-25 substrate peptide
Class: hydrolase
Keywords: Crystal structure, BoNT E, SNAP-25, Enzyme-substrate complex, HYDROLASE
Deposited on 2008-05-13, released 2008-07-08
The last revision prior to the SCOP 1.75 freeze date was dated 2008-10-21, with a file datestamp of 2008-10-17.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.235
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Type E botulinum toxin
    Species: Clostridium butyricum
    Gene: bont/E
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d3d3xa1
  • Chain 'B':
    Compound: Type E botulinum toxin
    Species: Clostridium butyricum
    Gene: bont/E
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d3d3xb1
  • Chain 'C':
    Compound: SNAP-25 substrate peptide
    Database cross-references and differences (RAF-indexed):
    • PDB 3D3X (0-End)
  • Chain 'D':
    Compound: SNAP-25 substrate peptide
    Database cross-references and differences (RAF-indexed):
    • PDB 3D3X (0-3)
  • Heterogens: ZN, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3d3xA (A:)
pkinsfnyndpvndrtilyikpggcqefyksfnimkniwiipernvigttpqdfhpptsl
kngdssyydpnylqsdeekdrflkivtkifnrinnnlsggilleelskanpylgndntpd
nqfhigdasaveikfsngsqdillpnviimgaepdlfetnssnislrnnympsnhgfgsi
aivtfspeysfrfndnsmnefiqdpaltlmhelihslhglygakgittkytitqkqnpli
tnirgtnieefltfggtdlniitsaqsndiytnlladykkiasklskvqvsnpllnpykd
vfeakygldkdasgiysvninkfndifkklysftefdlatkfqvkcrqtyigqykyfkls
nllndsiynisegyninnlkvnfrgqnanlnpriitpitgrglvkkiirfcknivsvkgi
rhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3d3xA (A:)
pkinsfnyndpvndrtilyikpggcqefyksfnimkniwiipernvigttpqdfhpptsl
kngdssyydpnylqsdeekdrflkivtkifnrinnnlsggilleelskanpylgndntpd
nqfhigdasaveikfsngsqdillpnviimgaepdlfetnssnislrnnympsnhgfgsi
aivtfspeysfrfndnsmnefiqdpaltlmhelihslhglygakgittkytitqlitnir
gtnieefltfggtdlniitsaqsndiytnlladykkiasklskvqvsnpllnpykdvfea
kygldkdasgiysvninkfndifkklysftefdlatkfqvkcrqtyigqykyfklsnlln
dsiynisegyninnlkvnfrgqnanlnpriitpitgrglvkkiirfc

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3d3xB (B:)
pkinsfnyndpvndrtilyikpggcqefyksfnimkniwiipernvigttpqdfhpptsl
kngdssyydpnylqsdeekdrflkivtkifnrinnnlsggilleelskanpylgndntpd
nqfhigdasaveikfsngsqdillpnviimgaepdlfetnssnislrnnympsnhgfgsi
aivtfspeysfrfndnsmnefiqdpaltlmhelihslhglygakgittkytitqkqnpli
tnirgtnieefltfggtdlniitsaqsndiytnlladykkiasklskvqvsnpllnpykd
vfeakygldkdasgiysvninkfndifkklysftefdlatkfqvkcrqtyigqykyfkls
nllndsiynisegyninnlkvnfrgqnanlnpriitpitgrglvkkiirfcknivsvkgi
rhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3d3xB (B:)
pkinsfnyndpvndrtilyikpggcqefyksfnimkniwiipernvigttpqdfhpptkn
gdssyydpnylqsdeekdrflkivtkifnrinnnlsggilleelskanpylgndntpdnq
fhigdasaveikfsngsqdillpnviimgaepdlfetnssnislrnnympsnhgfgsiai
vtfspeysfrfndnsmnefiqdpaltlmhelihslhglygakgittkytitqkqnplitn
irgtnieefltfggtdlniitsaqsndiytnlladykkiasklskvqvsnpllnpykdvf
eakygldkdasgiysvninkfndifkklysftefdlatkfqvkcrqtyigqykyfklsnl
lndsiynisegyninnlkvnfrgqnanlnpriitpitgrglvkkiir

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.