PDB entry 3cyn

View 3cyn on RCSB PDB site
Description: The structure of human GPX8
Class: oxidoreductase
Keywords: THIOREDOXIN FOLD, GLUTATHIONE PEROXIDASE, Membrane, Oxidoreductase, Transmembrane, Structural Genomics, Structural Genomics Consortium, SGC
Deposited on 2008-04-25, released 2008-08-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-31, with a file datestamp of 2018-01-26.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Probable glutathione peroxidase 8
    Species: Homo sapiens [TaxId:9606]
    Gene: LOC493869
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8TED1 (23-188)
      • expression tag (15-22)
    Domains in SCOPe 2.08: d3cyna1, d3cyna2
  • Chain 'B':
    Compound: Probable glutathione peroxidase 8
    Species: Homo sapiens [TaxId:9606]
    Gene: LOC493869
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8TED1 (23-188)
      • expression tag (16-22)
    Domains in SCOPe 2.08: d3cynb1, d3cynb2
  • Chain 'C':
    Compound: Probable glutathione peroxidase 8
    Species: Homo sapiens [TaxId:9606]
    Gene: LOC493869
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8TED1 (23-188)
      • expression tag (13-22)
    Domains in SCOPe 2.08: d3cync1, d3cync2
  • Heterogens: SO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3cynA (A:)
mhhhhhhssgvdlgtenlyfqsminsfyafevkdakgrtvslekykgkvslvvnvasdcq
ltdrnylglkelhkefgpshfsvlafpcnqfgeseprpskevesfarknygvtfpifhki
kilgsegepafrflvdsskkeprwnfwkylvnpegqvvkfwrpeepievirpdiaalvrq
viikkkedl

    Sequence, based on observed residues (ATOM records): (download) 
    >3cynA (A:)
enlyfqsminsfyafevkdakgrtvslekykgkvslvvnvasdcqltdrnylglkelhke
fgpshfsvlafpcnqfgeseprpskevesfarknygvtfpifhkikilgsegepafrflv
dsskkeprwnfwkylvnpegqvvkfwrpeepievirpdiaalvrqviikkkedl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3cynB (B:)
mhhhhhhssgvdlgtenlyfqsminsfyafevkdakgrtvslekykgkvslvvnvasdcq
ltdrnylglkelhkefgpshfsvlafpcnqfgeseprpskevesfarknygvtfpifhki
kilgsegepafrflvdsskkeprwnfwkylvnpegqvvkfwrpeepievirpdiaalvrq
viikkkedl

    Sequence, based on observed residues (ATOM records): (download) 
    >3cynB (B:)
nlyfqsminsfyafevkdakgrtvslekykgkvslvvnvasdcqltdrnylglkelhkef
gpshfsvlafpcnqfgeseprpskevesfarknygvtfpifhkikilgsegepafrflvd
sskkeprwnfwkylvnpegqvvkfwrpeepievirpdiaalvrqviikkkedl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3cynC (C:)
mhhhhhhssgvdlgtenlyfqsminsfyafevkdakgrtvslekykgkvslvvnvasdcq
ltdrnylglkelhkefgpshfsvlafpcnqfgeseprpskevesfarknygvtfpifhki
kilgsegepafrflvdsskkeprwnfwkylvnpegqvvkfwrpeepievirpdiaalvrq
viikkkedl

    Sequence, based on observed residues (ATOM records): (download) 
    >3cynC (C:)
gtenlyfqsminsfyafevkdakgrtvslekykgkvslvvnvasdcqltdrnylglkelh
kefgpshfsvlafpcnqfgeseprpskevesfarknygvtfpifhkikilgsegepafrf
lvdsskkeprwnfwkylvnpegqvvkfwrpeepievirpdiaalvrqviikkkedl