PDB entry 3clz
View 3clz on RCSB PDB site
Description: The set and ring associated (SRA) domain of UHRF1 bound to methylated DNA
Class: ligase
Keywords: CELL CYCLE, DNA DAMAGE, DNA REPAIR, DNA-BINDING, BASE FLIPPING, LIGASE, METAL BINDING, NUCLEASE, DNA REPLICATION, TRANSCRIPTIONAL SILENCING, CHROMATIN, PHOSPHORYLATION, TRANSCRIPTION, TRANSCRIPTION REGULATION, UBL CONJUGATION, UBL CONJUGATION PATHWAY, ZINC, ZINC-FINGER, STRUCTURAL GENOMICS CONSORTIUM, SGC, Metal-binding, Nucleus, Phosphoprotein, Polymorphism
Deposited on
2008-03-20, released
2008-04-29
The last revision prior to the SCOPe 2.03 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.191
AEROSPACI score: 0.38
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: E3 ubiquitin-protein ligase UHRF1
Species: Homo sapiens [TaxId:9606]
Gene: UHRF1, ICBP90, NP95, RNF106
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d3clza_ - Chain 'B':
Compound: E3 ubiquitin-protein ligase UHRF1
Species: Homo sapiens [TaxId:9606]
Gene: UHRF1, ICBP90, NP95, RNF106
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d3clzb_ - Chain 'C':
Compound: E3 ubiquitin-protein ligase UHRF1
Species: Homo sapiens [TaxId:9606]
Gene: UHRF1, ICBP90, NP95, RNF106
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d3clzc_ - Chain 'D':
Compound: E3 ubiquitin-protein ligase UHRF1
Species: Homo sapiens [TaxId:9606]
Gene: UHRF1, ICBP90, NP95, RNF106
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d3clzd_ - Chain 'E':
Compound: 5'-d(*dgp*dgp*dgp*dcp*dcp*(5cm)p*dgp*dcp*dap*dgp*dgp*dg)-3'
- Chain 'F':
Compound: 5'-d(*dcp*dcp*dcp*dtp*dgp*dcp*dgp*dgp*dgp*dcp*dcp*dc)-3'
- Chain 'G':
Compound: 5'-d(*dgp*dgp*dgp*dcp*dcp*(5cm)p*dgp*dcp*dap*dgp*dgp*dg)-3'
- Chain 'H':
Compound: 5'-d(*dcp*dcp*dcp*dtp*dgp*dcp*dgp*dgp*dgp*dcp*dcp*dc)-3'
- Chain 'I':
Compound: 5'-d(*dgp*dgp*dgp*dcp*dcp*(5cm)p*dgp*dcp*dap*dgp*dgp*dg)-3'
- Chain 'J':
Compound: 5'-d(*dcp*dcp*dcp*dtp*dgp*dcp*dgp*dgp*dgp*dcp*dcp*dc)-3'
- Chain 'K':
Compound: 5'-d(*dgp*dgp*dgp*dcp*dcp*(5cm)p*dgp*dcp*dap*dgp*dgp*dg)-3'
- Chain 'L':
Compound: 5'-d(*dcp*dcp*dcp*dtp*dgp*dcp*dgp*dgp*dgp*dcp*dcp*dc)-3'
- Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3clzA (A:)
mpsnhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdh
gnfftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrsgkp
vrvvrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtk
egkdrikklgltmqypegylealanahhhhhh
Sequence, based on observed residues (ATOM records): (download)
>3clzA (A:)
nhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdhgnf
ftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrsgkpvrv
vrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtkegk
drikklgltmqypegylealanah
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3clzB (B:)
mpsnhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdh
gnfftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrsgkp
vrvvrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtk
egkdrikklgltmqypegylealanahhhhhh
Sequence, based on observed residues (ATOM records): (download)
>3clzB (B:)
snhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdhgn
fftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrsgkpvr
vvrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtkeg
kdrikklgltmqypegylealanahhhhhh
- Chain 'C':
Sequence, based on SEQRES records: (download)
>3clzC (C:)
mpsnhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdh
gnfftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrsgkp
vrvvrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtk
egkdrikklgltmqypegylealanahhhhhh
Sequence, based on observed residues (ATOM records): (download)
>3clzC (C:)
nhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdhgnf
ftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrsgkpvrv
vrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtkegk
drikklgltmqypegylealanah
- Chain 'D':
Sequence, based on SEQRES records: (download)
>3clzD (D:)
mpsnhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdh
gnfftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrsgkp
vrvvrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtk
egkdrikklgltmqypegylealanahhhhhh
Sequence, based on observed residues (ATOM records): (download)
>3clzD (D:)
nhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdhgnf
ftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrsgkpvrv
vrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtkegk
drikklgltmqypegylealanahhhhhh
- Chain 'E':
No sequence available.
- Chain 'F':
No sequence available.
- Chain 'G':
No sequence available.
- Chain 'H':
No sequence available.
- Chain 'I':
No sequence available.
- Chain 'J':
No sequence available.
- Chain 'K':
No sequence available.
- Chain 'L':
No sequence available.