SCOPe 2.05: Structural Classification of Proteins

PDB entry 3cfk

View 3cfk on RCSB PDB site
Description: Crystal structure of catalytic elimination antibody 34E4, triclinic crystal form
Class: immune system
Keywords: IMMUNOGLOBULIN, CATALYTIC ANTIBODY, CHIMERIC FAB, APO FORM, PROTON TRANSFER, CONFORMATIONAL CHANGE, IMMUNE SYSTEM, CHIMERA, Immunoglobulin domain, Immunoglobulin V region
Deposited on 2008-03-04, released 2008-04-15
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.222
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Catalytic Antibody Fab 34E4 Light chain
Species: , [TaxId:10090,9606]
Gene: Igl-V1
Database cross-references and differences (RAF-indexed):
- PDB 3CFK (0-106)
- Uniprot Q8TCD0 (107-213)
Domains in SCOPe 2.05: d3cfka1, d3cfka2
Chain 'B':
Compound: Catalytic Antibody Fab 34E4 Heavy chain
Species: , [TaxId:10090,9606]
Database cross-references and differences (RAF-indexed):
- PDB 3CFK (0-112)
- Uniprot A8K008 (113-End)
  - engineered (117)
Domains in SCOPe 2.05: d3cfkb1, d3cfkb2
Chain 'C':
Compound: Catalytic Antibody Fab 34E4 Light chain
Species: , [TaxId:10090,9606]
Gene: Igl-V1
Database cross-references and differences (RAF-indexed):
- PDB 3CFK (0-106)
- Uniprot Q8TCD0 (107-213)
Domains in SCOPe 2.05: d3cfkc1, d3cfkc2
Chain 'D':
Compound: Catalytic Antibody Fab 34E4 Heavy chain
Species: , [TaxId:10090,9606]
Database cross-references and differences (RAF-indexed):
- PDB 3CFK (0-112)
- Uniprot A8K008 (113-End)
  - engineered (117)
Domains in SCOPe 2.05: d3cfkd1, d3cfkd2
Chain 'E':
Compound: Catalytic Antibody Fab 34E4 Light chain
Species: , [TaxId:10090,9606]
Gene: Igl-V1
Database cross-references and differences (RAF-indexed):
- PDB 3CFK (0-106)
- Uniprot Q8TCD0 (107-213)
Domains in SCOPe 2.05: d3cfke1, d3cfke2
Chain 'F':
Compound: Catalytic Antibody Fab 34E4 Heavy chain
Species: , [TaxId:10090,9606]
Database cross-references and differences (RAF-indexed):
- PDB 3CFK (0-112)
- Uniprot A8K008 (113-End)
  - engineered (117)
Domains in SCOPe 2.05: d3cfkf1, d3cfkf2
Chain 'G':
Compound: Catalytic Antibody Fab 34E4 Light chain
Species: , [TaxId:10090,9606]
Gene: Igl-V1
Database cross-references and differences (RAF-indexed):
- PDB 3CFK (0-106)
- Uniprot Q8TCD0 (107-213)
Domains in SCOPe 2.05: d3cfkg1, d3cfkg2
Chain 'H':
Compound: Catalytic Antibody Fab 34E4 Heavy chain
Species: , [TaxId:10090,9606]
Database cross-references and differences (RAF-indexed):
- PDB 3CFK (0-112)
- Uniprot A8K008 (113-End)
  - engineered (117)
Domains in SCOPe 2.05: d3cfkh1, d3cfkh2
Chain 'I':
Compound: Catalytic Antibody Fab 34E4 Heavy chain
Species: , [TaxId:10090,9606]
Database cross-references and differences (RAF-indexed):
- PDB 3CFK (0-112)
- Uniprot A8K008 (113-End)
  - engineered (117)
Domains in SCOPe 2.05: d3cfki1, d3cfki2
Chain 'J':
Compound: Catalytic Antibody Fab 34E4 Light chain
Species: , [TaxId:10090,9606]
Gene: Igl-V1
Database cross-references and differences (RAF-indexed):
- PDB 3CFK (0-106)
- Uniprot Q8TCD0 (107-213)
Domains in SCOPe 2.05: d3cfkj1, d3cfkj2
Chain 'K':
Compound: Catalytic Antibody Fab 34E4 Heavy chain
Species: , [TaxId:10090,9606]
Database cross-references and differences (RAF-indexed):
- PDB 3CFK (0-112)
- Uniprot A8K008 (113-End)
  - engineered (117)
Domains in SCOPe 2.05: d3cfkk1, d3cfkk2
Chain 'L':
Compound: Catalytic Antibody Fab 34E4 Light chain
Species: , [TaxId:10090,9606]
Gene: Igl-V1
Database cross-references and differences (RAF-indexed):
- PDB 3CFK (0-106)
- Uniprot Q8TCD0 (107-213)
Domains in SCOPe 2.05: d3cfkl1, d3cfkl2
Chain 'M':
Compound: Catalytic Antibody Fab 34E4 Light chain
Species: , [TaxId:10090,9606]
Gene: Igl-V1
Database cross-references and differences (RAF-indexed):
- PDB 3CFK (0-106)
- Uniprot Q8TCD0 (107-213)
Domains in SCOPe 2.05: d3cfkm1, d3cfkm2
Chain 'N':
Compound: Catalytic Antibody Fab 34E4 Heavy chain
Species: , [TaxId:10090,9606]
Database cross-references and differences (RAF-indexed):
- PDB 3CFK (0-112)
- Uniprot A8K008 (113-End)
  - engineered (117)
Domains in SCOPe 2.05: d3cfkn1, d3cfkn2
Chain 'O':
Compound: Catalytic Antibody Fab 34E4 Light chain
Species: , [TaxId:10090,9606]
Gene: Igl-V1
Database cross-references and differences (RAF-indexed):
- PDB 3CFK (0-106)
- Uniprot Q8TCD0 (107-213)
Domains in SCOPe 2.05: d3cfko1, d3cfko2
Chain 'P':
Compound: Catalytic Antibody Fab 34E4 Heavy chain
Species: , [TaxId:10090,9606]
Database cross-references and differences (RAF-indexed):
- PDB 3CFK (0-112)
- Uniprot A8K008 (113-End)
  - engineered (117)
Domains in SCOPe 2.05: d3cfkp1, d3cfkp2
Heterogens: CD, B3P, GOL, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>3cfkA (A:)
elvvtqesalttspgetvtltcrsssgavttsnyatwvqekpdhlftgliggtnkrapgv
parfsgsligdraaltitgaqtedeaiyfcalwnsnhlvfgggtkleikrtvaapsvfif
ppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsst
ltlskadyekhkvyacevthqglsspvtksfnrgec