PDB entry 3cen

View 3cen on RCSB PDB site
Description: Factor XA in complex with the inhibitor N-(2-(((5-chloro-2-pyridinyl) amino)sulfonyl)phenyl)-4-(2-oxo-1(2H)-pyridinyl)benzamide
Class: hydrolase
Keywords: glycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding, Cleavage on pair of basic residues, EGF-like domain, Gamma-carboxyglutamic acid, Hydroxylation, Polymorphism, Zymogen
Deposited on 2008-02-29, released 2008-05-20
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.251
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: coagulation factor x, heavy chain
  Species: HOMO SAPIENS
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00742 (0-233)
  Domains in SCOPe 2.04: d3cena_
• Chain 'L':
  Compound: coagulation factor x, light chain
  Species: HOMO SAPIENS
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00742 (0-51)
  Domains in SCOPe 2.04: d3cenl_
• Heterogens: FXA, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3cenA (A:)
  ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
  qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
  tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
  cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt
  

  
  
• Chain 'L':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3cenL (L:)
  klcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle