PDB entry 3c8n

View 3c8n on RCSB PDB site
Description: Crystal structure of apo-FGD1 from Mycobacterium tuberculosis
Class: oxidoreductase
Keywords: TIM barrel, non-prolyl cis-peptide, Oxidoreductase
Deposited on 2008-02-12, released 2008-04-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.214
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: probable f420-dependent glucose-6-phosphate dehydrogenase fgd1
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: fgd1, fgd, MT0420, Rv0407
    Database cross-references and differences (RAF-indexed):
    • Uniprot P96253 (20-End)
      • expression tag (7-17)
      • engineered (262)
    Domains in SCOPe 2.08: d3c8na1, d3c8na2
  • Chain 'B':
    Compound: probable f420-dependent glucose-6-phosphate dehydrogenase fgd1
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: fgd1, fgd, MT0420, Rv0407
    Database cross-references and differences (RAF-indexed):
    • Uniprot P96253 (20-End)
      • engineered (262)
    Domains in SCOPe 2.08: d3c8nb_
  • Chain 'C':
    Compound: probable f420-dependent glucose-6-phosphate dehydrogenase fgd1
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: fgd1, fgd, MT0420, Rv0407
    Database cross-references and differences (RAF-indexed):
    • Uniprot P96253
      • engineered (262)
    Domains in SCOPe 2.08: d3c8nc_
  • Chain 'D':
    Compound: probable f420-dependent glucose-6-phosphate dehydrogenase fgd1
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: fgd1, fgd, MT0420, Rv0407
    Database cross-references and differences (RAF-indexed):
    • Uniprot P96253
      • engineered (262)
    Domains in SCOPe 2.08: d3c8nd_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3c8nA (A:)
mgsshhhhhhssglvprgshmaelklgykasaeqfaprelvelavaaeahgmdsatvsdh
fqpwrhqgghapfslswmtavgertnrlllgtsvltptfrynpaviaqafatmgclypnr
vflgvgtgealneiatgyegawpefkerfarlresvglmrqlwsgdrvdfdgdyyrlkga
siydvpdggvpvyiaaggpavakyagragdgfictsgkgeelyteklmpavregaaaadr
svdgidkmieikisydpdpelamnntrfwaplsltaeqkhsiddpiemekaadalpieqi
akrwivasdpdeavekvgqyvtwglnhlvfhapghdqrrflelfqsdlaprlrrlg

    Sequence, based on observed residues (ATOM records): (download) 
    >3c8nA (A:)
hhhssglvprgmelklgykasaeqfaprelvelavaaeahgmdsatvsdhfqpwrhqggh
apfslswmtavgertnrlllgtsvltptfrynpaviaqafatmgclypnrvflgvgtgea
lneiatgyegawpefkerfarlresvglmrqlwsdrvdfdgdyyrlkgasiydvpdggvp
vyiaaggpavakyagragdgfictsgkgeelyteklmpavregaaaadrsvdgidkmiei
kisydpdpelamnntrfwaplsltaeqkhsiddpiemekaadalpieqiakrwivasdpd
eavekvgqyvtwglnhlvfhapghdqrrflelfqsdlaprlrr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3c8nB (B:)
mgsshhhhhhssglvprgshmaelklgykasaeqfaprelvelavaaeahgmdsatvsdh
fqpwrhqgghapfslswmtavgertnrlllgtsvltptfrynpaviaqafatmgclypnr
vflgvgtgealneiatgyegawpefkerfarlresvglmrqlwsgdrvdfdgdyyrlkga
siydvpdggvpvyiaaggpavakyagragdgfictsgkgeelyteklmpavregaaaadr
svdgidkmieikisydpdpelamnntrfwaplsltaeqkhsiddpiemekaadalpieqi
akrwivasdpdeavekvgqyvtwglnhlvfhapghdqrrflelfqsdlaprlrrlg

    Sequence, based on observed residues (ATOM records): (download) 
    >3c8nB (B:)
maelklgykasaeqfaprelvelavaaeahgmdsatvsdhfqphqgghapfslswmtavg
ertnrlllgtsvltptfrynpaviaqafatmgclypnrvflgvgtgealneiatgyegaw
pefkerfarlresvglmrqlwsgdrvdfdgdyyrlkgasiydvpdggvpvyiaaggpava
kyagragdgfictsgkgeelyteklmpavregaaaadrsvdgidkmieikisydpdpela
mnntrfwaplsltaeqkhsiddpiemekaadalpieqiakrwivasdpdeavekvgqyvt
wglnhlvfhapghdqrrflelfqsdlaprlrr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3c8nC (C:)
mgsshhhhhhssglvprgshmaelklgykasaeqfaprelvelavaaeahgmdsatvsdh
fqpwrhqgghapfslswmtavgertnrlllgtsvltptfrynpaviaqafatmgclypnr
vflgvgtgealneiatgyegawpefkerfarlresvglmrqlwsgdrvdfdgdyyrlkga
siydvpdggvpvyiaaggpavakyagragdgfictsgkgeelyteklmpavregaaaadr
svdgidkmieikisydpdpelamnntrfwaplsltaeqkhsiddpiemekaadalpieqi
akrwivasdpdeavekvgqyvtwglnhlvfhapghdqrrflelfqsdlaprlrrlg

    Sequence, based on observed residues (ATOM records): (download) 
    >3c8nC (C:)
elklgykasaeqfaprelvelavaaeahgmdsatvsdhfqpwrhqgghapfslswmtavg
ertnrlllgtsvltptfrynpaviaqafatmgclypnrvflgvgtgealneiatgyegaw
pefkerfarlresvglmrqlwsgdrvdfdgdyyrlkgasiydvpdggvpvyiaaggpava
kyagragdgfictsgkgeelyteklmpavregaaaadrsvdgidkmieikisydpdpela
mnntrfwaplsltaeqkhsiddpiemekaadalpieqiakrwivasdpdeavekvgqyvt
wglnhlvfhapghdqrrflelfqsdlaprlrr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3c8nD (D:)
mgsshhhhhhssglvprgshmaelklgykasaeqfaprelvelavaaeahgmdsatvsdh
fqpwrhqgghapfslswmtavgertnrlllgtsvltptfrynpaviaqafatmgclypnr
vflgvgtgealneiatgyegawpefkerfarlresvglmrqlwsgdrvdfdgdyyrlkga
siydvpdggvpvyiaaggpavakyagragdgfictsgkgeelyteklmpavregaaaadr
svdgidkmieikisydpdpelamnntrfwaplsltaeqkhsiddpiemekaadalpieqi
akrwivasdpdeavekvgqyvtwglnhlvfhapghdqrrflelfqsdlaprlrrlg

    Sequence, based on observed residues (ATOM records): (download) 
    >3c8nD (D:)
elklgykasaeqfaprelvelavaaeahgmdsatvsdhfqpwrhqgghapfslswmtavg
ertnrlllgtsvltptfrynpaviaqafatmgclypnrvflgvgtgealneiatgygawp
efkerfarlresvglmrqlwsdrvdfdgdyyrlkgasiydvpdggvpvyiaaggpavaky
agragdgfictsgkgeelyteklmpavregaaaadrsvdgidkmieikisydpdpelamn
ntrfwaplsltaeqkhsiddpiemekaadalpieqiakrwivasdpdeavekvgqyvtwg
lnhlvfhapghdqrrflelfqsdlaprlrr