PDB entry 3c7u

View 3c7u on RCSB PDB site
Description: Structural Insight into the Kinetics and Cp of interactions between TEM-1-Lactamase and BLIP
Class: hydrolase/hydrolase inhibitor
Keywords: enzyme-inhibitor complex, Antibiotic resistance, Hydrolase, Plasmid, Secreted, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
Deposited on 2008-02-08, released 2008-10-07
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-03-03, with a file datestamp of 2009-02-27.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.21
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Escherichia coli [TaxId:562]
    Gene: bla, blaTEM-116
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3c7ua_
  • Chain 'B':
    Compound: Beta-lactamase inhibitory protein
    Species: Streptomyces clavuligerus [TaxId:1901]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35804 (0-164)
      • engineered (149)
    Domains in SCOPe 2.05: d3c7ub_
  • Chain 'C':
    Compound: Beta-lactamase
    Species: Escherichia coli [TaxId:562]
    Gene: bla, blaTEM-116
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3c7uc_
  • Chain 'D':
    Compound: Beta-lactamase inhibitory protein
    Species: Streptomyces clavuligerus [TaxId:1901]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35804 (0-164)
      • engineered (149)
    Domains in SCOPe 2.05: d3c7ud_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3c7uA (A:)
hpetlvkvkdaedqlgarvgyieldlnsgkilesfrpeerfpmmstfkvllcgavlsrid
agqeqlgrrihysqndlveyspvtekhltdgmtvrelcsaaitmsdntaanlllttiggp
keltaflhnmgdhvtrldrwepelneaipnderdttmpvamattlrklltgelltlasrq
qlidwmeadkvagpllrsalpagwfiadksgagergsrgiiaalgpdgkpsrivviyttg
sqatmdernrqiaeigaslikhw

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3c7uB (B:)
agvmtgakftqiqfgmtrqqvldiagaencetggsfgdsihcrghaagdyyayatfgfts
aaadakvdsksqekllapsaptltlakfnqvtvgmtraqvlatvgqgscttwseyypayp
stagvtlslscfdvdgysstgfyrgsahlaftdgvlqgkrqwdlv

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3c7uC (C:)
hpetlvkvkdaedqlgarvgyieldlnsgkilesfrpeerfpmmstfkvllcgavlsrid
agqeqlgrrihysqndlveyspvtekhltdgmtvrelcsaaitmsdntaanlllttiggp
keltaflhnmgdhvtrldrwepelneaipnderdttmpvamattlrklltgelltlasrq
qlidwmeadkvagpllrsalpagwfiadksgagergsrgiiaalgpdgkpsrivviyttg
sqatmdernrqiaeigaslikhw

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3c7uD (D:)
agvmtgakftqiqfgmtrqqvldiagaencetggsfgdsihcrghaagdyyayatfgfts
aaadakvdsksqekllapsaptltlakfnqvtvgmtraqvlatvgqgscttwseyypayp
stagvtlslscfdvdgysstgfyrgsahlaftdgvlqgkrqwdlv