PDB entry 3c5z

View 3c5z on RCSB PDB site
Description: Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR B3K506
Class: sugar binding protein/immune system
Keywords: TCR-pMHC complex, Glycoprotein, Immune response, Membrane, MHC II, Transmembrane, SUGAR BINDING PROTEIN-IMMUNE SYSTEM COMPLEX
Deposited on 2008-02-01, released 2008-04-29
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-05-04, with a file datestamp of 2011-05-06.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: 0.246
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: TCR B3K506 Alpha Chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 3C5Z (0-201)
  • Chain 'B':
    Compound: TCR B3K506 Beta Chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 3C5Z (0-239)
  • Chain 'C':
    Compound: H-2 class II histocompatibility antigen, A-B alpha chain
    Species: Mus musculus [TaxId:10090]
    Gene: H2-Aa
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3c5zc1, d3c5zc2
  • Chain 'D':
    Compound: 3K peptide, Linker, and H-2 class II histocompatibility antigen (A beta chain)
    Species: Mus musculus [TaxId:10090]
    Gene: H2-Ab1, H2-iabeta
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14483 (Start-216)
      • linker (13)
      • engineered (215)
    • PDB 3C5Z (0-12)
    Domains in SCOPe 2.02: d3c5zd1, d3c5zd2
  • Chain 'E':
    Compound: TCR B3K506 Alpha Chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 3C5Z (0-End)
  • Chain 'F':
    Compound: TCR B3K506 Beta Chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 3C5Z (0-239)
  • Chain 'G':
    Compound: H-2 class II histocompatibility antigen, A-B alpha chain
    Species: Mus musculus [TaxId:10090]
    Gene: H2-Aa
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3c5zg1, d3c5zg2
  • Chain 'H':
    Compound: 3K peptide, Linker, and H-2 class II histocompatibility antigen (A beta chain)
    Species: Mus musculus [TaxId:10090]
    Gene: H2-Ab1, H2-iabeta
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14483 (Start-216)
      • linker (13)
      • engineered (215)
    • PDB 3C5Z (0-12)
    Domains in SCOPe 2.02: d3c5zh1, d3c5zh2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3c5zC (C:)
    ieadhvgtygisvyqspgdigqytfefdgdelfyvdldkketvwmlpefgqlasfdpqgg
    lqniavvkhnlgvltkrsnstpatneapqatvfpkspvllgqpntlicfvdnifppvini
    twlrnsksvadgvyetsffvnrdysfhklsyltfipsdddiydckvehwgleepvlkhwe
    pe
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >3c5zD (D:)
    feaqkakankavdggggslvprgsggggserhfvyqfmgecyftngtqriryvtryiynr
    eeyvrydsdvgehravtelgrpdaeywnsqpeilertraeldtvcrhnyegpethtslrr
    leqpnvvislsrtealnhhntlvcsvtdfypakikvrwfrngqeetvgvsstqlirngdw
    tfqvlvmlemtprrgevytchvehpslkspitvewka
    

    Sequence, based on observed residues (ATOM records): (download)
    >3c5zD (D:)
    feaqkakankavdgerhfvyqfmgecyftngtqriryvtryiynreeyvrydsdvgehra
    vtelgrpdaeywnsqpeilertraeldtvcrhnyegpethtslrrleqpnvvislsrtea
    lnhhntlvcsvtdfypakikvrwfrngqeetvgvsstqlirngdwtfqvlvmlemtprrg
    evytchvehpslkspitvewka
    

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3c5zG (G:)
    ieadhvgtygisvyqspgdigqytfefdgdelfyvdldkketvwmlpefgqlasfdpqgg
    lqniavvkhnlgvltkrsnstpatneapqatvfpkspvllgqpntlicfvdnifppvini
    twlrnsksvadgvyetsffvnrdysfhklsyltfipsdddiydckvehwgleepvlkhwe
    pe
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >3c5zH (H:)
    feaqkakankavdggggslvprgsggggserhfvyqfmgecyftngtqriryvtryiynr
    eeyvrydsdvgehravtelgrpdaeywnsqpeilertraeldtvcrhnyegpethtslrr
    leqpnvvislsrtealnhhntlvcsvtdfypakikvrwfrngqeetvgvsstqlirngdw
    tfqvlvmlemtprrgevytchvehpslkspitvewka
    

    Sequence, based on observed residues (ATOM records): (download)
    >3c5zH (H:)
    feaqkakankavdgerhfvyqfmgecyftngtqriryvtryiynreeyvrydsdvgehra
    vtelgrpdaeywnsqpeilertraeldtvcrhnyegpethtslrrleqpnvvislsrtea
    lnhhntlvcsvtdfypakikvrwfrngqeetvgvsstqlirngdwtfqvlvmlemtprrg
    evytchvehpslkspitvewka