PDB entry 3c5g

View 3c5g on RCSB PDB site
Description: Structure of a ternary complex of the R517K Pol lambda mutant
Class: Transferase/DNA, Lyase/DNA
Keywords: helix-hairpin-helix, DNA damage, DNA repair, DNA replication, DNA synthesis, DNA-binding, DNA-directed DNA polymerase, Lyase, Manganese, Metal-binding, Nucleotidyltransferase, Nucleus, Phosphoprotein, Transferase, Transferase/DNA, Lyase-DNA COMPLEX, Transferase-DNA
Deposited on 2008-01-31, released 2008-07-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase lambda
    Species: HOMO SAPIENS
    Gene: POLL
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UGP5 (Start-334)
      • engineered (276)
    Domains in SCOPe 2.07: d3c5ga1, d3c5ga2, d3c5ga3
  • Chain 'B':
    Compound: DNA polymerase lambda
    Species: HOMO SAPIENS
    Gene: POLL
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UGP5 (Start-334)
      • engineered (276)
    Domains in SCOPe 2.07: d3c5gb1, d3c5gb2, d3c5gb3
  • Chain 'D':
    Compound: DNA (5'-d(p*dgp*dcp*dcp*dg)-3')
  • Chain 'E':
    Compound: DNA (5'-d(p*dgp*dcp*dcp*dg)-3')
  • Chain 'P':
    Compound: DNA (5'-d(*dcp*dap*dgp*dtp*dap*(2dt))-3')
  • Chain 'Q':
    Compound: DNA (5'-d(*dcp*dap*dgp*dtp*dap*(2dt))-3')
  • Chain 'T':
    Compound: DNA (5'-d(*dcp*dgp*dgp*dcp*dap*dap*dtp*dap*dcp*dtp*dg)-3')
  • Chain 'U':
    Compound: DNA (5'-d(*dcp*dgp*dgp*dcp*dap*dap*dtp*dap*dcp*dtp*dg)-3')
  • Heterogens: MG, NA, D3T, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3c5gA (A:)
    maqpssqkatnhnlhiteklevlakaysvqgdkwralgyakainalksfhkpvtsyqeac
    sipgigkrmaekiieilesghlrkldhisesvpvlelfsniwgagtktaqmwyqqgfrsl
    edirsqaslttqqaiglkhysdflermpreeateieqtvqkaaqafnsgllcvacgsyrr
    gkatcgdvdvlithpdgrshrgifsrlldslrqegfltddlvsqeengqqqkylgvcrlp
    gpgrrhrrldiivvpysefacallyftgsahfnrsmkalaktkgmslsehalstavvrnt
    hgckvgpgrvlptptekdvfrllglpyrepaerdw
    

    Sequence, based on observed residues (ATOM records): (download)
    >3c5gA (A:)
    atnhnlhiteklevlakaysvqgdkwralgyakainalksfhkpvtsyqeacsipgigkr
    maekiieilesghlrkldhisesvpvlelfsniwgagtktaqmwyqqgfrsledirsqas
    lttqqaiglkhysdflermpreeateieqtvqkaaqafnsgllcvacgsyrrgkatcgdv
    dvlithpdgrshrgifsrlldslrqegfltddlvsqeengqqqkylgvcrlpgpgrrhrr
    ldiivvpysefacallyftgsahfnrsmkalaktkgmslsehalstavvhgckvgpgrvl
    ptptekdvfrllglpyrepaerdw
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3c5gB (B:)
    maqpssqkatnhnlhiteklevlakaysvqgdkwralgyakainalksfhkpvtsyqeac
    sipgigkrmaekiieilesghlrkldhisesvpvlelfsniwgagtktaqmwyqqgfrsl
    edirsqaslttqqaiglkhysdflermpreeateieqtvqkaaqafnsgllcvacgsyrr
    gkatcgdvdvlithpdgrshrgifsrlldslrqegfltddlvsqeengqqqkylgvcrlp
    gpgrrhrrldiivvpysefacallyftgsahfnrsmkalaktkgmslsehalstavvrnt
    hgckvgpgrvlptptekdvfrllglpyrepaerdw
    

    Sequence, based on observed residues (ATOM records): (download)
    >3c5gB (B:)
    ssqkatnhnlhiteklevlakaysvqgdkwralgyakainalksfhkpvtsyqeacsipg
    igkrmaekiieilesghlrkldhisesvpvlelfsniwgagtktaqmwyqqgfrsledir
    sqaslttqqaiglkhysdflermpreeateieqtvqkaaqafnsgllcvacgsyrrgkat
    cgdvdvlithpdgrshrgifsrlldslrqegfltddlvsqeengqqqkylgvcrlpgpgr
    rhrrldiivvpysefacallyftgsahfnrsmkalaktkgmslsehalstavvrhgckvg
    pgrvlptptekdvfrllglpyrepaerdw
    

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    No sequence available.

  • Chain 'T':
    No sequence available.

  • Chain 'U':
    No sequence available.