PDB entry 3c5c

View 3c5c on RCSB PDB site
Description: Crystal structure of human Ras-like, family 12 protein in complex with GDP
Class: signaling protein
Keywords: ras, rasl12, gdp, gtpase, Structural Genomics Consortium, SGC, limited proteolysis, GTP-binding, Nucleotide-binding, SIGNALING PROTEIN
Deposited on 2008-01-31, released 2008-02-12
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.203
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: RAS-like protein 12
    Species: Homo sapiens [TaxId:9606]
    Gene: RASL12, RIS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3c5ca_
  • Chain 'B':
    Compound: RAS-like protein 12
    Species: Homo sapiens [TaxId:9606]
    Gene: RASL12, RIS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3c5cb_
  • Chain 'C':
    Compound: RAS-like protein 12
    Species: Homo sapiens [TaxId:9606]
    Gene: RASL12, RIS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NYN1 (18-End)
      • expression tag (17)
    Domains in SCOPe 2.05: d3c5cc_
  • Chain 'D':
    Compound: RAS-like protein 12
    Species: Homo sapiens [TaxId:9606]
    Gene: RASL12, RIS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3c5cd_
  • Heterogens: MG, GDP, UNX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3c5cA (A:)
mhhhhhhssgrenlyfqgplevnlailgrrgagksaltvkfltkrfiseydpnledtyss
eetvdhqpvhlrvmdtadldtprncerylnwahaflvvysvdsrqsfdssssylellalh
aketqrsipalllgnkldmaqyrqvtkaegvalagrfgclffevsacldfehvqhvfhea
vrearre

    Sequence, based on observed residues (ATOM records): (download) 
    >3c5cA (A:)
levnlailgrrgagksaltvkfltkrfiseydpnledtysseetvdhqpvhlrvmdtadp
rncerylnwahaflvvysvdsrqsfdssssylellalhaketqrsipalllgnkldmaqy
rqvtkaegvalagrfgclffevsacldfehvqhvfheavrearr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3c5cB (B:)
mhhhhhhssgrenlyfqgplevnlailgrrgagksaltvkfltkrfiseydpnledtyss
eetvdhqpvhlrvmdtadldtprncerylnwahaflvvysvdsrqsfdssssylellalh
aketqrsipalllgnkldmaqyrqvtkaegvalagrfgclffevsacldfehvqhvfhea
vrearre

    Sequence, based on observed residues (ATOM records): (download) 
    >3c5cB (B:)
levnlailgrrgagksaltvkfltkrfiseydpnledtysseetvdhqpvhlrvmdtadl
dtprncerylnwahaflvvysvdsrqsfdssssylellalhaketqrsipalllgnkldm
aqyrqvtkaegvalagrfgclffevsacldfehvqhvfheavrearr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3c5cC (C:)
mhhhhhhssgrenlyfqgplevnlailgrrgagksaltvkfltkrfiseydpnledtyss
eetvdhqpvhlrvmdtadldtprncerylnwahaflvvysvdsrqsfdssssylellalh
aketqrsipalllgnkldmaqyrqvtkaegvalagrfgclffevsacldfehvqhvfhea
vrearre

    Sequence, based on observed residues (ATOM records): (download) 
    >3c5cC (C:)
gplevnlailgrrgagksaltvkfltkrfiseydpnledtysseetvdhqpvhlrvmdta
dlprncerylnwahaflvvysvdsrqsfdssssylellalhaketqpalllgnkldmaqy
rqvtkaegvalagrfgclffevsacldfehvqhvfheavrearr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3c5cD (D:)
mhhhhhhssgrenlyfqgplevnlailgrrgagksaltvkfltkrfiseydpnledtyss
eetvdhqpvhlrvmdtadldtprncerylnwahaflvvysvdsrqsfdssssylellalh
aketqrsipalllgnkldmaqyrqvtkaegvalagrfgclffevsacldfehvqhvfhea
vrearre

    Sequence, based on observed residues (ATOM records): (download) 
    >3c5cD (D:)
levnlailgrrgagksaltvkfltkrfiseydpnledtysseetvdhqpvhlrvmdtadl
rncerylnwahaflvvysvdsrqsfdssssylellalhaketqrsipalllgnkldmaqy
rqvtkaegvalagrfgclffevsacldfehvqhvfheavrearr