PDB entry 3c49

View 3c49 on RCSB PDB site
Description: Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor KU0058948
Class: transferase
Keywords: enzyme-inhibitor complex, catalytic fragment, Structural Genomics, Structural Genomics Consortium, SGC, Alternative splicing, Glycosyltransferase, NAD, Nucleus, Transferase
Deposited on 2008-01-29, released 2008-02-12
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-06-16, with a file datestamp of 2009-06-12.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.191
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Poly(ADP-ribose) polymerase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: PARP3, ADPRT3, ADPRTL3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y6F1 (2-356)
      • expression tag (0-1)
    Domains in SCOPe 2.03: d3c49a1, d3c49a2
  • Heterogens: KU8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3c49A (A:)
smkrvqpcsldpatqklitnifskemfkntmalmdldvkkmplgklskqqiargfealea
leealkgptdggqsleelsshfytviphnfghsqpppinspellqakkdmllvladiela
qalqavseqektveevphpldrdyqllkcqlqlldsgapeykviqtyleqtgsnhrcptl
qhiwkvnqegeedrfqahsklgnrkllwhgtnmavvaailtsglrimphsggrvgkgiyf
asensksagyvigmkcgahhvgymflgevalgrehhintdnpslkspppgfdsviarght
epdptqdteleldgqqvvvpqgqpvpcpefssstfsqseyliyqesqcrlryllevh