PDB entry 3bx7
View 3bx7 on RCSB PDB site
Description: Engineered Human Lipocalin 2 (LCN2) in Complex with the Extracellular Domain of Human CTLA-4
Class: de novo protein, protein binding
Keywords: protein design, protein-protein complex, glycoprotein, immunoglobulin domain, polymorphism, transmembrane protein, de novo protein, protein binding
Deposited on
2008-01-11, released
2009-01-20
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-01-20, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.209
AEROSPACI score: 0.41
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: engineered human lipocalin 2
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3bx7a_ - Chain 'C':
Compound: cytotoxic t-lymphocyte-associated antigen 4
Species: HOMO SAPIENS
Gene: CTLA4, CD152
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3bx7c_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3bx7A (A:)
qdstsdlipapplskvplqqnfqdnqfhgkwyvvglagnrilrddqhpmnmyatiyelke
dksynvtsvisshkkceytiatfvpgsqpgeftlgniksygdktsylvrvvstdynqyav
vffklaednaeffaitiygrtkelaselkenfirfskslglpenhivfpvpidqcidg
Sequence, based on observed residues (ATOM records): (download)
>3bx7A (A:)
dlipapplskvplqqnfqdnqfhgkwyvvglagnrilrddqhpmnmyatiyelkedksyn
vtsvisshkkceytiatfvpgsqpgeftlgniksygdktsylvrvvstdynqyavvffkl
aednaeffaitiygrtkelaselkenfirfskslglpenhivfpvpidqcidg
- Chain 'C':
Sequence, based on SEQRES records: (download)
>3bx7C (C:)
mhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgneltf
lddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvidpepc
pdsd
Sequence, based on observed residues (ATOM records): (download)
>3bx7C (C:)
mhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgneltf
lddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvidpepc