PDB entry 3bpn

View 3bpn on RCSB PDB site
Description: Crystal structure of the IL4-IL4R-IL13Ra ternary complex
Class: Cytokine/Cytokine receptor
Keywords: IL4, IL13, IL13R, IL4R, cytokine, receptor, B-cell activation, Glycoprotein, Growth factor, Secreted, Immune response, Membrane, Phosphoprotein, Transmembrane, Cytokine-Cytokine receptor COMPLEX
Deposited on 2007-12-18, released 2008-02-05
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 3.02 Å
R-factor: 0.238
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: interleukin-4
    Species: Homo sapiens [TaxId:9606]
    Gene: IL4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3bpna_
  • Chain 'B':
    Compound: Interleukin-4 receptor alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: IL4R, 582J2.1, IL4RA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24394 (4-End)
      • expression tag (2-3)
      • engineered (30)
      • engineered (75)
      • engineered (111)
      • engineered (153)
    Domains in SCOPe 2.06: d3bpnb1, d3bpnb2, d3bpnb3
  • Chain 'C':
    Compound: Interleukin-13 receptor alpha-1 chain
    Species: Homo sapiens [TaxId:9606]
    Gene: IL13RA1, IL13R, IL13RA
    Database cross-references and differences (RAF-indexed):
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3bpnA (A:)
hkcditlqeiiktlnslteqktlcteltvtdifaaskntteketfcraatvlrqfyshhe
kdtrclgataqqfhrhkqlirflkrldrnlwglaglnscpvkeanqstlenflerlktim
rekyskcss

    Sequence, based on observed residues (ATOM records): (download) 
    >3bpnA (A:)
cditlqeiiktlnslteqktlcteltvtdifaaskntteketfcraatvlrqfyshhekd
trclgataqqfhrhkqlirflkrldrnlwglaglnscpvkeanqstlenflerlktimre
kyskcs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3bpnB (B:)
adpfkvlqeptcvsdymsistcewkmngptqcstelrllyqlvfllseahtcipenngga
gcvchllmddvvsadqytldlwagqqllwkgsfkpsehvkprapgnltvhtqvsdtlllt
wsnpyppdnylynhltyavniwsendpadfriyqvtylepslriaastlksgisyrarvr
awaqcynttwsewspstkwhnsyre

    Sequence, based on observed residues (ATOM records): (download) 
    >3bpnB (B:)
pfkvlqeptcvsdymsistcewkmngptqcstelrllyqlvfllseahtcipennggagc
vchllmddvvsadqytldlwagqqllwkgsfkpsehvkprapgnltvhtqvsdtllltws
npyppdnylynhltyavniwsendpadfriyqvtylepslriaastlksgisyrarvraw
aqcynttwsewspstkwhn

  • Chain 'C':
    No sequence available.