PDB entry 3bmy

View 3bmy on RCSB PDB site
Description: Discovery of Benzisoxazoles as Potent Inhibitors of Chaperone Hsp90
Class: Chaperone
Keywords: Chaperone, ATP binding domain, Alternative splicing, ATP-binding, Cytoplasm, Nucleotide-binding, Phosphoprotein, Stress response
Deposited on 2007-12-13, released 2008-07-08
The last revision prior to the SCOP 1.75 freeze date was dated 2008-07-08, with a file datestamp of 2008-07-03.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.194
AEROSPACI score: 0.69 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heat shock protein HSP 90-alpha
    Species: HOMO SAPIENS
    Gene: HSP90AA1, HSP90A, HSPC1, HSPCA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d3bmya1
  • Heterogens: CXZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3bmyA (A:)
qpmeeevetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskl
dsgkelhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadism
igqfgvgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhl
kedqteyleerrikeivkkhsqfigypitlfvekerdkevsddeae

    Sequence, based on observed residues (ATOM records): (download) 
    >3bmyA (A:)
qpmeeevetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskl
dsgkelhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadism
igqfgvgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhl
kedqteyleerrikeivkkhsqfigypitlfve