PDB entry 3biz

View 3biz on RCSB PDB site
Description: Wee1 kinase complex with inhibitor PD331618
Class: transferase
Keywords: kinase domain, inhibitor complex, ATP-binding, Cell cycle, Cell division, Magnesium, Metal-binding, Mitosis, Nucleotide-binding, Nucleus, Phosphoprotein, Transferase, Tyrosine-protein kinase
Deposited on 2007-12-02, released 2007-12-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Wee1-like protein kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: WEE1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3biza_
  • Heterogens: CL, 61E, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3bizA (A:)
gamksryttefhelekigsgefgsvfkcvkrldgciyaikrskkplagsvdeqnalrevy
ahavlgqhshvvryfsawaeddhmliqneycnggsladaisenyrimsyfkeaelkdlll
qvgrglryihsmslvhmdikpsnifisrtsipnaaseegdeddwasnkvmfkigdlghvt
risspqveegdsrflanevlqenythlpkadifalaltvvcaagaeplprngdqwheirq
grlpripqvlsqeftellkvmihpdperrpsamalvkhsvllsasrk

    Sequence, based on observed residues (ATOM records): (download) 
    >3bizA (A:)
sryttefhelekigssvfkcvkrldgciyaikrskkpsvdeqnalrevyahavlgqhshv
vryfsawaeddhmliqneycnggsladaisenyrimsyfkeaelkdlllqvgrglryihs
mslvhmdikpsnifiskvmfkigdlghvtrisspqveegdsrflanevlqenythlpkad
ifalaltvvcaagaeplprngdqwheirqgrlpripqvlsqeftellkvmihpdperrps
amalvkhsvl