PDB entry 3bim

View 3bim on RCSB PDB site
Description: Crystal structure of the BCL6 BTB domain dimer in complex with the BCOR BBD corepressor peptide
Class: transcription repressor
Keywords: protein-peptide compex, Activator, Chromosomal rearrangement, DNA-binding, Metal-binding, Nucleus, Phosphoprotein, Polymorphism, Proto-oncogene, Repressor, Transcription, Transcription regulation, Zinc, Zinc-finger, Alternative splicing, ANK repeat, Chromatin regulator, Disease mutation, TRANSCRIPTION REPRESSOR
Deposited on 2007-11-30, released 2008-01-08
The last revision prior to the SCOPe 2.02 freeze date was dated 2010-01-19, with a file datestamp of 2010-01-15.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.221
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41182 (2-126)
      • engineered (5)
      • engineered (64)
      • engineered (81)
    Domains in SCOPe 2.02: d3bima_
  • Chain 'B':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41182 (2-End)
      • engineered (5)
      • engineered (64)
      • engineered (81)
    Domains in SCOPe 2.02: d3bimb_
  • Chain 'C':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41182 (2-126)
      • engineered (5)
      • engineered (64)
      • engineered (81)
    Domains in SCOPe 2.02: d3bimc_
  • Chain 'D':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41182 (2-End)
      • engineered (5)
      • engineered (64)
      • engineered (81)
    Domains in SCOPe 2.02: d3bimd_
  • Chain 'E':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41182
      • engineered (5)
      • engineered (64)
      • engineered (81)
    Domains in SCOPe 2.02: d3bime_
  • Chain 'F':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41182 (2-End)
      • engineered (5)
      • engineered (64)
      • engineered (81)
    Domains in SCOPe 2.02: d3bimf_
  • Chain 'G':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41182
      • engineered (5)
      • engineered (64)
      • engineered (81)
    Domains in SCOPe 2.02: d3bimg_
  • Chain 'H':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41182
      • engineered (5)
      • engineered (64)
      • engineered (81)
    Domains in SCOPe 2.02: d3bimh_
  • Chain 'I':
    Compound: BCL-6 corepressor
    Species: Homo sapiens [TaxId:9606]
    Gene: BCOR
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: BCL-6 corepressor
    Species: Homo sapiens [TaxId:9606]
    Gene: BCOR
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: BCL-6 corepressor
    Species: Homo sapiens [TaxId:9606]
    Gene: BCOR
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: BCL-6 corepressor
    Species: Homo sapiens [TaxId:9606]
    Gene: BCOR
    Database cross-references and differences (RAF-indexed):
  • Chain 'M':
    Compound: BCL-6 corepressor
    Species: Homo sapiens [TaxId:9606]
    Gene: BCOR
    Database cross-references and differences (RAF-indexed):
  • Chain 'N':
    Compound: BCL-6 corepressor
    Species: Homo sapiens [TaxId:9606]
    Gene: BCOR
    Database cross-references and differences (RAF-indexed):
  • Chain 'O':
    Compound: BCL-6 corepressor
    Species: Homo sapiens [TaxId:9606]
    Gene: BCOR
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: BCL-6 corepressor
    Species: Homo sapiens [TaxId:9606]
    Gene: BCOR
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3bimA (A:)
gsadsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysift
dqlkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcr
kfikase

    Sequence, based on observed residues (ATOM records): (download) 
    >3bimA (A:)
adsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdq
lkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcrkf
ikase

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3bimB (B:)
gsadsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysift
dqlkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcr
kfikase

    Sequence, based on observed residues (ATOM records): (download) 
    >3bimB (B:)
adsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdq
lkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcrkf
ikas

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3bimC (C:)
gsadsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysift
dqlkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcr
kfikase

    Sequence, based on observed residues (ATOM records): (download) 
    >3bimC (C:)
adsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdq
lkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcrkf
ikase

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3bimD (D:)
gsadsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysift
dqlkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcr
kfikase

    Sequence, based on observed residues (ATOM records): (download) 
    >3bimD (D:)
adsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdq
lkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcrkf
ikas

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3bimE (E:)
gsadsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysift
dqlkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcr
kfikase

    Sequence, based on observed residues (ATOM records): (download) 
    >3bimE (E:)
dsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdql
krnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcrkfi
kas

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3bimF (F:)
gsadsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysift
dqlkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcr
kfikase

    Sequence, based on observed residues (ATOM records): (download) 
    >3bimF (F:)
adsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdq
lkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcrkf
ik

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >3bimG (G:)
gsadsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysift
dqlkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcr
kfikase

    Sequence, based on observed residues (ATOM records): (download) 
    >3bimG (G:)
sqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlk
rnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcrkfik
as

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >3bimH (H:)
gsadsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysift
dqlkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcr
kfikase

    Sequence, based on observed residues (ATOM records): (download) 
    >3bimH (H:)
dsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdql
krnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcrkfi
ka

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    No sequence available.

  • Chain 'K':
    No sequence available.

  • Chain 'L':
    No sequence available.

  • Chain 'M':
    No sequence available.

  • Chain 'N':
    No sequence available.

  • Chain 'O':
    No sequence available.

  • Chain 'P':
    No sequence available.