PDB entry 3bel

View 3bel on RCSB PDB site
Description: X-ray structure of EGFR in complex with oxime inhibitor
Class: transferase
Keywords: kinase domain, Alternative splicing, Anti-oncogene, ATP-binding, Cell cycle, Disease mutation, Glycoprotein, Membrane, Nucleotide-binding, Phosphoprotein, Polymorphism, Receptor, Secreted, Transferase, Transmembrane, Tyrosine-protein kinase, Ubl conjugation
Deposited on 2007-11-19, released 2008-07-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Epidermal growth factor receptor
    Species: Homo sapiens
    Gene: EGFR, ERBB1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3bela_
  • Heterogens: PO4, POX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3belA (A:)
allrilketefkkikvlgsgafgtvykglwipegekvkipvaikelreatspkankeild
eayvmasvdnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsqyllnwcvqi
akgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhaeggkvpikwm
alesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekgerlpqppicti
dvymimvkcwmidadsrpkfreliiefskmardpqrylviqgdermhlpsptdsnfyral
mdeedmddvvdadey

    Sequence, based on observed residues (ATOM records): (download) 
    >3belA (A:)
allrilketefkkikvlgsgafgtvykglwipvkipvaikelkankeildeayvmasvdn
phvcrllgicltstvqlitqlmpfgclldyvrehkdnigsqyllnwcvqiakgmnyledr
rlvhrdlaarnvlvktpqhvkitdfglakllgaeekvpikwmalesilhriythqsdvws
ygvtvwelmtfgskpydgipaseissilekgerlpqppictidvymimvkcwmidadsrp
kfreliiefskmardpqrylviqgdernfyralmvvdade