PDB entry 3bc7
View 3bc7 on RCSB PDB site
Description: The carbohydrate recognition domain of Langerin reveals high structural similarity with the one of DC-SIGN but an additional, calcium-independent sugar-binding site
Class: immune system
Keywords: calcium-binding, CRD, DC-SIGN, Langerin, lectin, maltose binding, Glycoprotein, LONG LOOP REGION, MEMBRANE PROTEIN, SUGAR-BINDING, TRANSMEMBRANE PROTEIN, IMMUNE SYSTEM, CARBOHYDRATE BINDING PROTEIN
Deposited on
2007-11-12, released
2007-12-25
The last revision prior to the SCOPe 2.06 freeze date was dated
2010-11-03, with a file datestamp of
2010-10-29.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.22
AEROSPACI score: 0.55
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: C-type lectin domain family 4 member K
Species: Homo sapiens [TaxId:9606]
Gene: langerin
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3bc7a_ - Chain 'B':
Compound: C-type lectin domain family 4 member K
Species: Homo sapiens [TaxId:9606]
Gene: langerin
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3bc7b_ - Chain 'C':
Compound: C-type lectin domain family 4 member K
Species: Homo sapiens [TaxId:9606]
Gene: langerin
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3bc7c_ - Chain 'D':
Compound: C-type lectin domain family 4 member K
Species: Homo sapiens [TaxId:9606]
Gene: langerin
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3bc7d_ - Heterogens: MAN, CA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>3bc7A (A:)
qgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliywiglt
kagmegdwswvddtpfnkvqsvrfwipgepnnagnnehcgnikapslqawndapcdktfl
fickrpyvp
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3bc7B (B:)
qgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliywiglt
kagmegdwswvddtpfnkvqsvrfwipgepnnagnnehcgnikapslqawndapcdktfl
fickrpyvp
Sequence, based on observed residues (ATOM records): (download)
>3bc7B (B:)
gwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliywigltk
agdwswvddtpfnkvqsvrfwipgepnnagnnehcgnikapslqawndapcdktflfick
rpyvp
- Chain 'C':
Sequence, based on SEQRES records: (download)
>3bc7C (C:)
qgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliywiglt
kagmegdwswvddtpfnkvqsvrfwipgepnnagnnehcgnikapslqawndapcdktfl
fickrpyvp
Sequence, based on observed residues (ATOM records): (download)
>3bc7C (C:)
gwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliywigltk
agmegdwswvddtpfnkvqsvrfwipgepnnagnnehcgnikapslqawndapcdktflf
ickrpyvp
- Chain 'D':
Sequence, based on SEQRES records: (download)
>3bc7D (D:)
qgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliywiglt
kagmegdwswvddtpfnkvqsvrfwipgepnnagnnehcgnikapslqawndapcdktfl
fickrpyvp
Sequence, based on observed residues (ATOM records): (download)
>3bc7D (D:)
gwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqeflyktaggliywigltk
agmegdwswvddtpfnkvqsvrfwipgepnnagnnehcgnikapslqawndapcdktflf
ickrpyvp