PDB entry 3bar

View 3bar on RCSB PDB site
Description: Crystal structure of Plasmodium falciparum orotidine 5'-phosphate decarboxylase covalently modified by 6-azido-UMP
Class: lyase
Keywords: Plasmodium falciparum, orotidine 5'-phosphate decarboxylase, covalently, 6-azido-UMP, Lyase, Pyrimidine biosynthesis
Deposited on 2007-11-08, released 2008-01-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.174
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: orotidine 5'-phosphate decarboxylase
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Gene: ompdc
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8T6J6 (19-End)
      • expression tag (17-18)
    Domains in SCOPe 2.08: d3bara2, d3bara3
  • Chain 'B':
    Compound: orotidine 5'-phosphate decarboxylase
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Gene: ompdc
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8T6J6 (19-End)
      • expression tag (18)
    Domains in SCOPe 2.08: d3barb2, d3barb3
  • Heterogens: U5P, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3barA (A:)
mgsshhhhhhssglvprgsmgfkvklekrrnaintclcigldpdekdienfmknekenny
nnikknlkekyinnvsikkdillkapdniireekseeffyffnhfcfyiinetnkyaltf
kmnfafyipygsvgidvlknvfdylyelniptildmkindigntvknyrkfifeylksds
ctvniymgtnmlkdicydeeknkyysafvlvkttnpdsaifqknlsldnkqayvimaqea
lnmssylnleqnnefigfvvgansydemnyirtyfpncyilspgigaqngdlhktltngy
hksyekilinigraitknpypqkaaqmyydqinailkqnmes

    Sequence, based on observed residues (ATOM records): (download) 
    >3barA (A:)
gsmgfkvklekrrnaintclcigldpdekdienfmknekennynnikknlkekyinnvsi
kkdillkapdniireekseeffyffnhfcfyiinetnkyaltfkmnfafyipygsvgidv
lknvfdylyelniptildmkindigntvknyrkfifeylksdsctvniymgtnmlkdicy
deeknkyysafvlvkttnpdsaifqknlsldnkqayvimaqealnmssylnleqnnefig
fvvgansydemnyirtyfpncyilspgigaqngdlhktltngyhksyekilinigraitk
npypqkaaqmyydqinailkqnm

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3barB (B:)
mgsshhhhhhssglvprgsmgfkvklekrrnaintclcigldpdekdienfmknekenny
nnikknlkekyinnvsikkdillkapdniireekseeffyffnhfcfyiinetnkyaltf
kmnfafyipygsvgidvlknvfdylyelniptildmkindigntvknyrkfifeylksds
ctvniymgtnmlkdicydeeknkyysafvlvkttnpdsaifqknlsldnkqayvimaqea
lnmssylnleqnnefigfvvgansydemnyirtyfpncyilspgigaqngdlhktltngy
hksyekilinigraitknpypqkaaqmyydqinailkqnmes

    Sequence, based on observed residues (ATOM records): (download) 
    >3barB (B:)
smgfkvklekrrnaintclcigldpdekdienfmknekennynnikknlkekyinnvsik
kdillkapdniireekseeffyffnhfcfyiinetnkyaltfkmnfafyipygsvgidvl
knvfdylyelniptildmkindigntvknyrkfifeylksdsctvniymgtnmlkdicyd
eeknkyysafvlvkttnpdsaifqknlsldnkqayvimaqealnmssylnleqnnefigf
vvgansydemnyirtyfpncyilspgigaqngdlhktltngyhksyekilinigraitkn
pypqkaaqmyydqinailkqnm