PDB entry 3b3i

View 3b3i on RCSB PDB site
Description: Citrullination-dependent differential presentation of a self-peptide by HLA-B27 subtypes
Class: immune system
Keywords: HLA-B2709, ankylosing spondylitis, Glycoprotein, Host-virus interaction, Immune response, Membrane, MHC I, Transmembrane, Disease mutation, Glycation, Immunoglobulin domain, Pyrrolidone carboxylic acid, Secreted, G-protein coupled receptor, Phosphorylation, Receptor, Transducer, PROTEIN BINDING, IMMUNE SYSTEM
Deposited on 2007-10-22, released 2008-07-22
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.86 Å
R-factor: 0.191
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, B-27 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-B, HLAB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03989 (0-275)
      • variant (115)
    Domains in SCOPe 2.06: d3b3ia1, d3b3ia2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.06: d3b3ib2, d3b3ib3
  • Chain 'C':
    Compound: vasoactive intestinal polypeptide receptor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: VIPR1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3b3iA (A:)
    gshsmryfhtsvsrpgrgeprfitvgyvddtlfvrfdsdaaspreeprapwieqegpeyw
    dretqickakaqtdredlrtllryynqseagshtlqnmygcdvgpdgrllrgyhqhaydg
    kdyialnedlsswtaadtaaqitqrkweaarvaeqlraylegecvewlrrylengketlq
    radppkthvthhpisdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdrt
    fqkwaavvvpsgeeqrytchvqheglpkpltlrwep
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3b3iB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.