PDB entry 3aqv
View 3aqv on RCSB PDB site
Description: Human AMP-activated protein kinase alpha 2 subunit kinase domain (T172D) complexed with compound C
Class: transferase/transferase inhibitor
Keywords: Structural Genomics, RIKEN Structural Genomics/Proteomics Initiative, RSGI, Transferase, Signaling protein, Serine/threonine protein kinase, Phosphorylation, ATP-binding, Nucleotide-binding, Cholesterol biosynthesis, Fatty acid biosynthesis, Lipid synthesis, glucose metabolism, Magnesium, Metal-binding, Serine/threonine-protein kinase, Steroid biosynthesis, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on
2010-11-19, released
2011-04-27
The last revision prior to the SCOPe 2.08 freeze date was dated
2012-04-11, with a file datestamp of
2012-04-06.
Experiment type: XRAY
Resolution: 2.08 Å
R-factor: 0.224
AEROSPACI score: 0.38
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: 5'-AMP-activated protein kinase catalytic subunit alpha-2
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3aqva_ - Heterogens: TAK, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3aqvA (A:)
gskhdgrvkighyvlgdtlgvgtfgkvkigehqltghkvavkilnrqkirsldvvgkikr
eiqnlklfrhphiiklyqvistptdffmvmeyvsggelfdyickhgrveemearrlfqqi
lsavdychrhmvvhrdlkpenvlldahmnakiadfglsnmmsdgeflrdscgspnyaape
visgrlyagpevdiwscgvilyallcgtlpfddehvptlfkkirggvfyipeylnrsvat
llmhmlqvdplkratikdirehewfkqdlpsylfpe
Sequence, based on observed residues (ATOM records): (download)
>3aqvA (A:)
hdgrvkighyvlgdtlgvgtfgkvkigehqltghkvavkilnrqkirsldvvgkikreiq
nlklfrhphiiklyqvistptdffmvmeyvsggelfdyickhgrveemearrlfqqilsa
vdychrhmvvhrdlkpenvlldahmnakiadfglsnmmsdgeflpnyaapevisgrlyag
pevdiwscgvilyallcgtlpfddehvptlfkkirggvfyipeylnrsvatllmhmlqvd
plkratikdirehewfkqdlpsylfpe