PDB entry 3aln

View 3aln on RCSB PDB site
Description: Crystal Structure of human non-phosphorylated MKK4 kinase domain complexed with AMP-PNP
Class: transferase
Keywords: kinase, protein amp-pnp complex, transferase
Deposited on 2010-08-04, released 2010-10-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dual specificity mitogen-activated protein kinase kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: JNKK1, MAP2K4, MEK4, MKK4, PRKMK4, SERK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3alna_
  • Chain 'B':
    Compound: Dual specificity mitogen-activated protein kinase kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: JNKK1, MAP2K4, MEK4, MKK4, PRKMK4, SERK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3alnb_
  • Chain 'C':
    Compound: Dual specificity mitogen-activated protein kinase kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: JNKK1, MAP2K4, MEK4, MKK4, PRKMK4, SERK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3alnc_
  • Heterogens: ANP, MG

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3alnA (A:)
msiessgklkispeqhwdftaedlkdlgeigrgaygsvnkmvhkpsgqimavkrirstvd
ekeqkqllmdldvvmrssdcpyivqfygalfregdcwicmelmstsfdkfykyvysvldd
vipeeilgkitlatvkalnhlkenlkiihrdikpsnilldrsgniklcdfgisgqlvdsi
aktrdagcrpymaperidpsasrqgydvrsdvwslgitlyelatgrfpypkwnsvfdqlt
qvvkgdppqlsnseerefspsfinfvnlcltkdeskrpkykellkhpfilmyeeraveva
cyvckildqmpatpsspmyvdhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3alnA (A:)
ssgklkispeqhwdftaedlkdlgeigrgaygsvnkmvhkpsgqimavkrirstvdekeq
kqllmdldvvmrssdcpyivqfygalfregdcwicmelmstsfdkfykyvysvlddvipe
eilgkitlatvkalnhlkenlkiihrdikpsnilldrsgniklcdfgisgqydvrsdvws
lgitlyelatgrfpypkwtqvvkgdppqlsnseerefspsfinfvnlcltkdeskrpkyk
ellkhpfilmyeeravevacyvckildqmp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3alnB (B:)
msiessgklkispeqhwdftaedlkdlgeigrgaygsvnkmvhkpsgqimavkrirstvd
ekeqkqllmdldvvmrssdcpyivqfygalfregdcwicmelmstsfdkfykyvysvldd
vipeeilgkitlatvkalnhlkenlkiihrdikpsnilldrsgniklcdfgisgqlvdsi
aktrdagcrpymaperidpsasrqgydvrsdvwslgitlyelatgrfpypkwnsvfdqlt
qvvkgdppqlsnseerefspsfinfvnlcltkdeskrpkykellkhpfilmyeeraveva
cyvckildqmpatpsspmyvdhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3alnB (B:)
sgklkispeqhwdftaedlkdlgeigrgaygsvnkmvhkpsgqimavkrirstvdekeqk
qllmdldvvmrssdcpyivqfygalfregdcwicmelmstsfdkfykyvysvlddvipee
ilgkitlatvkalnhlkenlkiihrdikpsnilldrsgniklcdfgisgqlydvrsdvws
lgitlyelatgrfpypdppqlsnseerefspsfinfvnlcltkdeskrpkykellkhpfi
lmyeeravevacyvckildqmpa

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3alnC (C:)
msiessgklkispeqhwdftaedlkdlgeigrgaygsvnkmvhkpsgqimavkrirstvd
ekeqkqllmdldvvmrssdcpyivqfygalfregdcwicmelmstsfdkfykyvysvldd
vipeeilgkitlatvkalnhlkenlkiihrdikpsnilldrsgniklcdfgisgqlvdsi
aktrdagcrpymaperidpsasrqgydvrsdvwslgitlyelatgrfpypkwnsvfdqlt
qvvkgdppqlsnseerefspsfinfvnlcltkdeskrpkykellkhpfilmyeeraveva
cyvckildqmpatpsspmyvdhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3alnC (C:)
edlkdlgenkmvimavkrirstcpyivqfycwicmelmstsfdkfykyvysvlddvipee
ilgkitlatvkalnhlkenlkkpsnilldrsgniklcdfsdvwslgitlyelatgrfppq
lsnseerefspsfinfvnlcltkdeskrpkykellkhpfilmyeeravevacyvckildq
mpa