PDB entry 3a99

View 3a99 on RCSB PDB site
Description: Structure of PIM-1 kinase crystallized in the presence of P27KIP1 Carboxy-terminal peptide
Class: transferase
Keywords: Pim-1, p27Kip1, peptide drug, prostate cancer, TRANSFERASE
Deposited on 2009-10-22, released 2010-11-03
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-03-30, with a file datestamp of 2011-03-25.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.187
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Proto-oncogene serine/threonine-protein kinase Pim-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PIM1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3a99a_
  • Heterogens: MG, ANP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3a99A (A:)
mgsshhhhhhssglvprgshmapcndlhatklapgkekeplesqyqvgpllgsggfgsvy
sgirvsdnlpvaikhvekdrisdwgelpngtrvpmevvllkkvssgfsgvirlldwferp
dsfvlilerpepvqdlfdfitergalqeelarsffwqvleavrhchncgvlhrdikdeni
lidlnrgelklidfgsgallkdtvytdfdgtrvysppewiryhryhgrsaavwslgilly
dmvcgdipfehdeeiirgqvffrqrvssecqhlirwclalrpsdrptfeeiqnhpwmqdv
llpqetaeihlhslspgpsk

    Sequence, based on observed residues (ATOM records): (download) 
    >3a99A (A:)
plesqyqvgpllgsggfgsvysgirvsdnlpvaikhvekdrisdwgelpngtrvpmevvl
lkkvssgfsgvirlldwferpdsfvlilerpepvqdlfdfitergalqeelarsffwqvl
eavrhchncgvlhrdikdenilidlnrgelklidfgsgallkdtvytdfdgtrvysppew
iryhryhgrsaavwslgillydmvcgdipfehdeeiirgqvffrqrvssecqhlirwcla
lrpsdrptfeeiqnhpwmqdvllpqetaeihlh