PDB entry 3a62

View 3a62 on RCSB PDB site
Description: Crystal structure of phosphorylated p70S6K1
Class: transferase
Keywords: Kinase, Kinase domain, Inactive, Active, Ribosomal S6 kinase, Activation, Alternative initiation, ATP-binding, Cell junction, Cytoplasm, Nucleotide-binding, Phosphoprotein, Polymorphism, Serine/threonine-protein kinase, Synapse, Synaptosome, Transferase
Deposited on 2009-08-18, released 2009-10-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-03-02, with a file datestamp of 2010-02-26.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.229
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ribosomal protein S6 kinase beta-1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3a62a_
  • Heterogens: STU, MN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3a62A (A:)
    gssetsvnrgpekirpecfellrvlgkggygkvfqvrkvtgantgkifamkvlkkamivr
    nakdtahtkaernileevkhpfivdliyafqtggklylileylsggelfmqleregifme
    dtacfylaeismalghlhqkgiiyrdlkpenimlnhqghvkltdfglckesihdgtvtht
    fcgtieymapeilmrsghnravdwwslgalmydmltgappftgenrkktidkilkcklnl
    ppyltqeardllkkllkrnaasrlgagpgdagevqahpffrhinweellarkveppfkpl
    lqseedvsqfdskftrqtpvdspddst
    

    Sequence, based on observed residues (ATOM records): (download)
    >3a62A (A:)
    kirpecfellrvlgkggygkvfqvrkvtgantgkifamkvlkkaernileevkhpfivdl
    iyafqtggklylileylsggelfmqleregifmedtacfylaeismalghlhqkgiiyrd
    lkpenimlnhqghvkltdfglchtfcgtieymapeilmrsghnravdwwslgalmydmlt
    gappftgenrkktidkilkcklnlppyltqeardllkkllkrnaasrlgagpgdagevqa
    hpffrhinweellarkveppfkpl