PDB entry 3a60

View 3a60 on RCSB PDB site
Description: Crystal structure of unphosphorylated p70S6K1 (Form I)
Class: transferase
Keywords: Kinase, Kinase domain, Inactive, Active, Ribosomal S6 kinase, Activation, Alternative initiation, ATP-binding, Cell junction, Cytoplasm, Nucleotide-binding, Phosphoprotein, Polymorphism, Serine/threonine-protein kinase, Synapse, Synaptosome, Transferase
Deposited on 2009-08-17, released 2009-10-27
The last revision prior to the SCOPe 2.06 freeze date was dated 2010-03-02, with a file datestamp of 2010-02-26.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.21
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ribosomal protein S6 kinase beta-1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3a60a_
  • Chain 'B':
    Compound: Ribosomal protein S6 kinase beta-1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3a60b_
  • Heterogens: STU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3a60A (A:)
gssetsvnrgpekirpecfellrvlgkggygkvfqvrkvtgantgkifamkvlkkamivr
nakdtahtkaernileevkhpfivdliyafqtggklylileylsggelfmqleregifme
dtacfylaeismalghlhqkgiiyrdlkpenimlnhqghvkltdfglckesihdgtvtht
fcgtieymapeilmrsghnravdwwslgalmydmltgappftgenrkktidkilkcklnl
ppyltqeardllkkllkrnaasrlgagpgdagevqahpffrhinweellarkveppfkpl
lqseedvsqfdskftrqtpvdspddst

    Sequence, based on observed residues (ATOM records): (download) 
    >3a60A (A:)
kirpecfellrvlgkggygkvfqvrkvtgantgkifamkvlkkamkaernileevkhpfi
vdliyafqtggklylileylsggelfmqleregifmedtacfylaeismalghlhqkgii
yrdlkpenimlnhqghvkltdfglcketieymapeilmrsghnravdwwslgalmydmlt
gappftgenrkktidkilkcklnlppyltqeardllkkllkrnaasrlgagpgdagevqa
hpffrhinweellarkveppfkp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3a60B (B:)
gssetsvnrgpekirpecfellrvlgkggygkvfqvrkvtgantgkifamkvlkkamivr
nakdtahtkaernileevkhpfivdliyafqtggklylileylsggelfmqleregifme
dtacfylaeismalghlhqkgiiyrdlkpenimlnhqghvkltdfglckesihdgtvtht
fcgtieymapeilmrsghnravdwwslgalmydmltgappftgenrkktidkilkcklnl
ppyltqeardllkkllkrnaasrlgagpgdagevqahpffrhinweellarkveppfkpl
lqseedvsqfdskftrqtpvdspddst

    Sequence, based on observed residues (ATOM records): (download) 
    >3a60B (B:)
kirpecfellrvlgkggygkvfqvrkvtgantgkifamkvlkkkhpfivdliyafqtggk
lylileylsggelfmqleregifmedtacfylaeismalghlhqkgiiyrdlkpenimln
hqghvkltdfglckescgtieymapeilmrsghnravdwwslgalmydmltgappftgen
rkktidkilkcklnlppyltqeardllkkllkrnaasrlgagpgdagevqahpffrhinw
eellarkveppfkpl