PDB entry 3a5k

View 3a5k on RCSB PDB site
Description: Crystal structure of protein-tyrosine phosphatase 1B
Class: hydrolase
Keywords: alpha/beta structure C121W mutant, HYDROLASE
Deposited on 2009-08-08, released 2010-08-11
The last revision prior to the SCOPe 2.04 freeze date was dated 2010-08-11, with a file datestamp of 2010-08-06.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.191
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tyrosine-protein phosphatase non-receptor type 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P18031
      • engineered mutation (126)
    Domains in SCOPe 2.04: d3a5ka_
  • Heterogens: MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3a5kA (A:)
mhhhhhhemekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdh
sriklhqedndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvm
ekgslkwaqywpqkeekemifedtnlkltlisediksyytvrqlelenlttqetreilhf
hyttwpdfgvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclll
mdkrkdpssvdikkvllemrkfrmgliqtadqlrfsylaviegakfimgdssvqdqwkel
shed

    Sequence, based on observed residues (ATOM records): (download) 
    >3a5kA (A:)
mekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdhsriklhqe
dndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgslkwa
qywpqkeekemifedtnlkltlisediksyytvrqlelenlttqetreilhfhyttwpdf
gvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclllmdkrkdps
svdikkvllemrkfrmgliqtadqlrfsylaviegakfimg