PDB entry 2zzu

View 2zzu on RCSB PDB site
Description: Human Factor VIIA-Tissue Factor Complexed with ethylsulfonamide-D-5-(3-carboxybenzyloxy)-Trp-Gln-p-aminobenzamidine
Class: hydrolase/blood clotting
Keywords: serine protease, blood coagulation, cleavage on pair of basic residues, disease mutation, egf-like domain, gamma-carboxyglutamic acid, glycoprotein, hydrolase, hydroxylation, protease, zymogen, lipoprotein, membrane, palmitate, transmembrane, hydrolase-blood clotting complex, secreted
Deposited on 2009-02-25, released 2009-03-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Factor VII heavy chain
    Species: Homo sapiens [TaxId:9606]
    Gene: F7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2zzuh_
  • Chain 'L':
    Compound: Factor VII light chain
    Species: Homo sapiens [TaxId:9606]
    Gene: F7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2zzul1, d2zzul2, d2zzul3
  • Chain 'T':
    Compound: tissue factor
    Species: Homo sapiens [TaxId:9606]
    Gene: F3
    Database cross-references and differences (RAF-indexed):
  • Heterogens: BGC, FUC, CA, 359, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2zzuH (H:)
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >2zzuL (L:)
anafleelrpgslereckeeqcsfeeareifkdaertklfwisysdgdqcasspcqnggs
ckdqlqsyicfclpafegrncethkddqlicvnenggceqycsdhtgtkrscrchegysl
ladgvsctptveypcgkipilekrnaskpqgr

    Sequence, based on observed residues (ATOM records): (download) 
    >2zzuL (L:)
anafleelrpgslereckeeqcsfeeareifkdaertklfwisysdgdqcasspcqnggs
ckdqlqsyicfclpafegrncethkddqlicvnenggceqycsdhtgtkrscrchegysl
ladgvsctptveypcgkipile

  • Chain 'T':
    No sequence available.