PDB entry 2zva

View 2zva on RCSB PDB site
Description: Lyn Tyrosine Kinase Domain-Dasatinib complex
Class: transferase
Keywords: Lyn Kinase dasatinib, ATP-binding, Kinase, Lipoprotein, Myristate, Nucleotide-binding, Palmitate, Phosphoprotein, Proto-oncogene, SH2 domain, SH3 domain, Transferase, Tyrosine-protein kinase
Deposited on 2008-11-04, released 2008-11-11
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.199
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tyrosine-protein kinase lyn
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25911 (5-End)
      • expression tag (4)
    Domains in SCOPe 2.06: d2zvaa1, d2zvaa2
  • Heterogens: 1N1, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2zvaA (A:)
gamdpaweipresiklvkklgagqfgevwmgyynnstkvavktlkpgtmsvqafleeanl
mktlqhdklvrlyavvtkeepiyiitefmakgslldflksdeggkvllpklidfsaqiae
gmayierknyihrdlraanvlvseslmckiadfglarviedneytaregakfpikwtape
ainfgcftiksnvwsfgillyeivtygkipypgrtnadvmsalsqgyrmprmencpdely
dimkmcwkekaeerptfdylqsvlddfytategqyqqqp

    Sequence, based on observed residues (ATOM records): (download) 
    >2zvaA (A:)
paweipresiklvkklgagqfgevwmgyynnstkvavktlkpgtmsvqafleeanlmktl
qhdklvrlyavvtkeepiyiitefmakgslldflksdeggkvllpklidfsaqiaegmay
ierknyihrdlraanvlvseslmckiadfglarvietaregakfpikwtapeainfgcft
iksnvwsfgillyeivtygkipypgrtnadvmsalsqgyrmprmencpdelydimkmcwk
ekaeerptfdylqsvlddfyt