PDB entry 2zp0
View 2zp0 on RCSB PDB site
Description: Human factor viia-tissue factor complexed with benzylsulfonamide-D-ile-gln-P-aminobenzamidine
Class: hydrolase/blood clotting
Keywords: SERINE PROTEASE, Alternative splicing, Blood coagulation, Calcium, Cleavage on pair of basic residues, Disease mutation, EGF-like domain, Gamma-carboxyglutamic acid, Glycoprotein, Hydrolase, Hydroxylation, Pharmaceutical, Polymorphism, Protease, Zymogen, Lipoprotein, Membrane, Palmitate, Transmembrane, HYDROLASE/BLOOD CLOTTING COMPLEX
Deposited on
2008-06-20, released
2008-07-15
The last revision prior to the SCOP 1.75 freeze date was dated
2008-07-15, with a file datestamp of
2008-07-11.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.218
AEROSPACI score: 0.35
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: Factor VII heavy chain
Species: Homo sapiens [TaxId:9606]
Gene: F7
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d2zp0h1 - Chain 'L':
Compound: Factor VII light chain
Species: Homo sapiens [TaxId:9606]
Gene: F7
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d2zp0l1, d2zp0l2, d2zp0l3 - Chain 'T':
Compound: tissue factor
Species: Homo sapiens [TaxId:9606]
Gene: F3
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d2zp0t1, d2zp0t2 - Heterogens: BGC, FUC, CA, PI0, HOH
PDB Chain Sequences:
- Chain 'H':
Sequence; same for both SEQRES and ATOM records: (download)
>2zp0H (H:)
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp
- Chain 'L':
Sequence, based on SEQRES records: (download)
>2zp0L (L:)
anafleelrpgslereckeeqcsfeeareifkdaertklfwisysdgdqcasspcqnggs
ckdqlqsyicfclpafegrncethkddqlicvnenggceqycsdhtgtkrscrchegysl
ladgvsctptveypcgkipilekrnaskpqgr
Sequence, based on observed residues (ATOM records): (download)
>2zp0L (L:)
anafleelrpgslereckeeqcsfeeareifkdaertklfwisysdgdqcasspcqnggs
ckdqlqsyicfclpafegrncethkddqlicvnenggceqycsdhtgtkrscrchegysl
ladgvsctptveypcgkipile
- Chain 'T':
Sequence, based on SEQRES records: (download)
>2zp0T (T:)
sgttntvaaynltwkstnfktilewepkpvnqvytvqistksgdwkskcfyttdtecdlt
deivkdvkqtylarvfsypagnvestgsageplyenspeftpyletnlgqptiqsfeqvg
tkvnvtvedertlvrrnntflslrdvfgkdliytlyywkssssgkktaktntneflidvd
kgenycfsvqavipsrtvnrkstdspvecmgqekgefr
Sequence, based on observed residues (ATOM records): (download)
>2zp0T (T:)
tvaaynltwkstnfktilewepkpvnqvytvqistksgdwkskcfyttdtecdltdeivk
dvkqtylarvfsypeplyenspeftpyletnlgqptiqsfeqvgtkvnvtvedertlvrr
nntflslrdvfgkdliytlyywksgkktaktntneflidvdkgenycfsvqavipsrtvn
rkstdspvecm