PDB entry 2znu

View 2znu on RCSB PDB site
Description: Crystal structure of the ligand-binding core of the human ionotropic glutamate receptor, GluR5, in complex with a novel selective agonist, neodysiherbaine A
Class: membrane protein
Keywords: GluR5, ligand-binding core, neodysiherbaine A, agonist, Alternative splicing, Cell junction, Glycoprotein, Ion transport, Ionic channel, Membrane, Phosphoprotein, Polymorphism, Postsynaptic cell membrane, RNA editing, Synapse, Transmembrane, Transport, MEMBRANE PROTEIN
Deposited on 2008-05-01, released 2009-05-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-08-16, with a file datestamp of 2017-08-11.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor, ionotropic kainate 1
    Species: Homo sapiens [TaxId:9606]
    Gene: Grik1, Glur5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P39086 (0-114)
      • linker (115-116)
    • Uniprot P39086 (117-End)
    Domains in SCOPe 2.08: d2znua_
  • Heterogens: NDZ, BME, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2znuA (A:)
anrtlivttileepyvmyrksdkplygndrfegycldllkelsnilgfiydvklvpdgky
gaqndkgewngmvkelidhradlavapltityvrekvidfskpfmtlgisilyrkgtpid
saddlakqtkieygavrdgstmtffkkskistyekmwafmssrqqtalvrnsdegiqrvl
ttdyallmestsieyvtqrncnltqigglidskgygvgtpigspyrdkitiailqlqeeg
klhmmkekwwrgngcp

    Sequence, based on observed residues (ATOM records): (download) 
    >2znuA (A:)
anrtlivttileepyvmyrksdkplygndrfegycldllkelsnilgfiydvklvpdgky
gaqndkgewngmvkelidhradlavapltityvrekvidfskpfmtlgisilyrkgtpid
saddlakqtkieygavrdgstmtffkkskistyekmwafmssrqqtalvrnsdegiqrvl
ttdyallmestsieyvtqrncnltqigglidskgygvgtpigspyrdkitiailqlqeeg
klhmmkekwwrgngc