PDB entry 2z7l

View 2z7l on RCSB PDB site
Description: Unphosphorylated Mitogen Activated Protein Kinase ERK2 in Complex with (4-{[5-Carbamoyl-4-(3-Methylanilino)Pyrimidin 2-Yl]Amino}Phenyl)Acetic Acid
Class: transferase
Keywords: TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, CELL CYCLE, PHOSPHORYLATION, Acetylation, Nucleotide-binding
Deposited on 2007-08-27, released 2008-08-12
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.41 Å
R-factor: 0.223
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Mapk1, Erk2, Mapk, Prkm1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2z7la_
  • Heterogens: SO4, S91, BME, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2z7lA (A:)
mahhhhhhmaaaaaagpemvrgqvfdvgprytnlsyigegaygmvcsaydnlnkvrvaik
kispfehqtycqrtlreikillrfrheniigindiiraptieqmkdvyivqdlmetdlyk
llktqhlsndhicyflyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarva
dpdhdhtgflteyvatrwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyl
dqlnhilgilgspsqedlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkml
tfnphkrieveqalahpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarf
qpgyrs

    Sequence, based on observed residues (ATOM records): (download) 
    >2z7lA (A:)
vfdvgprytnlsyigegmvcsaydnlnkvrvaikkispfehqtycqrtlreikillrfrh
eniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicyflyqilrglkyi
hsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyvatrwyrapeiml
nskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedlnciinlka
rnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpyleqyydps
depiaeapflpkeklkelifeetarfqpg