PDB entry 2z3y

View 2z3y on RCSB PDB site
Description: Crystal structure of Lysine-specific demethylase1
Class: oxidoreductase
Keywords: chromatin, crystal structure, histone demethylase, nucleosome, transcription, LSD1, Lysine-specific, Alternative splicing, Chromatin regulator, Coiled coil, FAD, Nucleus, Oxidoreductase, Phosphorylation, Repressor, Transcription regulation, Structural Genomics, NPPSFA, National Project on Protein Structural and Functional Analyses, RIKEN Structural Genomics/Proteomics Initiative, RSGI
Deposited on 2007-06-08, released 2008-01-01
The last revision prior to the SCOP 1.75 freeze date was dated 2008-01-01, with a file datestamp of 2007-12-28.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.218
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lysine-specific histone demethylase 1
    Species: HOMO SAPIENS
    Gene: KIAA0601, LSD1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2z3ya1, d2z3ya2, d2z3ya3
  • Heterogens: F2N, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2z3yA (A:)
sgvegaafqsrlphdrmtsqeaacfpdiisgpqqtqkvflfirnrtlqlwldnpkiqltf
eatlqqleapynsdtvlvhrvhsylerhglinfgiykrikplptkktgkviiigsgvsgl
aaarqlqsfgmdvtlleardrvggrvatfrkgnyvadlgamvvtglggnpmavvskqvnm
elakikqkcplyeangqavpkekdemveqefnrlleatsylshqldfnvlnnkpvslgqa
levviqlqekhvkdeqiehwkkivktqeelkellnkmvnlkekikelhqqykeasevkpp
rditaeflvkskhrdltalckeydelaetqgkleeklqeleanppsdvylssrdrqildw
hfanlefanatplstlslkhwdqdddfeftgshltvrngyscvpvalaegldiklntavr
qvrytasgceviavntrstsqtfiykcdavlctlplgvlkqqppavqfvpplpewktsav
qrmgfgnlnkvvlcfdrvfwdpsvnlfghvgsttasrgelflfwnlykapillalvagea
agimenisddvivgrclailkgifgssavpqpketvvsrwradpwargsysyvaagssgn
dydlmaqpitpgpsipgapqpiprlffagehtirnypatvhgallsglreagriadqflg
am

    Sequence, based on observed residues (ATOM records): (download) 
    >2z3yA (A:)
sgvegaafqsrlphdrmtsqeaacfpdiisgpqqtqkvflfirnrtlqlwldnpkiqltf
eatlqqleapynsdtvlvhrvhsylerhglinfgiykrikplptkktgkviiigsgvsgl
aaarqlqsfgmdvtlleardrvggrvatfrkgnyvadlgamvvtglggnpmavvskqvnm
elakikqkcplyeangqavpkekdemveqefnrlleatsylshqldfnvlnnkpvslgqa
levviqlqekhvkdeqiehwkkivktqeelkellnkmvnlkekikelhqqykeditaefl
vkskhrdltalckeydelaetqgkleeklqeleanppsdvylssrdrqildwhfanlefa
natplstlslkhwdqdddfeftgshltvrngyscvpvalaegldiklntavrqvrytasg
ceviavntrstsqtfiykcdavlctlplgvlkqqppavqfvpplpewktsavqrmgfgnl
nkvvlcfdrvfwdpsvnlfghvgsttasrgelflfwnlykapillalvageaagimenis
ddvivgrclailkgifgssavpqpketvvsrwradpwargsysyvaagssgndydlmaqp
itppiprlffagehtirnypatvhgallsglreagriadqflg