PDB entry 2z3q

View 2z3q on RCSB PDB site
Description: Crystal structure of the IL-15/IL-15Ra complex
Class: cytokine/cytokine receptor
Keywords: Protein-Protein complex, CYTOKINE/CYTOKINE RECEPTOR COMPLEX
Deposited on 2007-06-05, released 2007-09-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.205
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Interleukin-15
    Species: Homo sapiens [TaxId:9606]
    Gene: IL15
    Database cross-references and differences (RAF-indexed):
    • Uniprot P40933 (5-118)
      • expression tag (0-4)
    Domains in SCOPe 2.08: d2z3qa1, d2z3qa2
  • Chain 'B':
    Compound: Interleukin-15 receptor alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: IL15RA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13261 (5-End)
      • expression tag (2-4)
    Domains in SCOPe 2.08: d2z3qb1, d2z3qb2
  • Chain 'C':
    Compound: Interleukin-15
    Species: Homo sapiens [TaxId:9606]
    Gene: IL15
    Database cross-references and differences (RAF-indexed):
    • Uniprot P40933 (5-End)
      • expression tag (0-4)
    Domains in SCOPe 2.08: d2z3qc2, d2z3qc3
  • Chain 'D':
    Compound: Interleukin-15 receptor alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: IL15RA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13261 (5-End)
      • expression tag (1-4)
    Domains in SCOPe 2.08: d2z3qd2, d2z3qd3
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2z3qA (A:)
    amaisnwvnvisdlkkiedliqsmhidatlytesdvhpsckvtamkcfllelqvislesg
    dasihdtvenliilannslssngnvtesgckeceeleeknikeflqsfvhivqmfints
    

    Sequence, based on observed residues (ATOM records): (download)
    >2z3qA (A:)
    amaisnwvnvisdlkkiedliqsmhidatlytesdvhpsckvtamkcfllelqvislesg
    dasihdtvenliilannslstesgckeceeleeknikeflqsfvhivqmfints
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2z3qB (B:)
    amaisitcpppmsvehadiwvksyslysreryicnsgfkrkagtssltecvlnkatnvah
    wttpslkcirdpalvhqrpappstvttagvtpqpeslspsgkepaas
    

    Sequence, based on observed residues (ATOM records): (download)
    >2z3qB (B:)
    aisitcpppmsvehadiwvksyslysreryicnsgfkrkagtssltecvlnkatnvahwt
    tpslkcirdpalvhqrpapps
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2z3qC (C:)
    amaisnwvnvisdlkkiedliqsmhidatlytesdvhpsckvtamkcfllelqvislesg
    dasihdtvenliilannslssngnvtesgckeceeleeknikeflqsfvhivqmfints
    

    Sequence, based on observed residues (ATOM records): (download)
    >2z3qC (C:)
    amaisnwvnvisdlkkiedliqsmhidatlytesdvhpsckvtamkcfllelqvislesg
    dasihdtvenliilannslssngnvtesgckeceeleeknikeflqsfvhivqmfin
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >2z3qD (D:)
    amaisitcpppmsvehadiwvksyslysreryicnsgfkrkagtssltecvlnkatnvah
    wttpslkcirdpalvhqrpappstvttagvtpqpeslspsgkepaas
    

    Sequence, based on observed residues (ATOM records): (download)
    >2z3qD (D:)
    maisitcpppmsvehadiwvksyslysreryicnsgfkrkagtssltecvlnkatnvahw
    ttpslkcirdpalvhqr