PDB entry 2ynh

View 2ynh on RCSB PDB site
Description: HIV-1 Reverse Transcriptase in complex with inhibitor GSK500
Class: hydrolase
Keywords: hydrolase, nnrti
Deposited on 2012-10-14, released 2013-01-09
The last revision prior to the SCOPe 2.04 freeze date was dated 2013-12-18, with a file datestamp of 2013-12-13.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.20848
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Reverse transcriptase/ribonuclease H
    Species: HIV-1 M:B_HXB2R [TaxId:11706]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04585 (3-End)
      • expression tag (1-2)
    Domains in SCOPe 2.04: d2ynha1, d2ynha2
  • Chain 'B':
    Compound: p51 RT
    Species: HIV-1 M:B_HXB2R [TaxId:11706]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2ynhb_
  • Heterogens: TAR, EUR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ynhA (A:)
mnspispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyn
tpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfs
vpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpd
iviyqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpd
kwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplte
eaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarm
rgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefv
ntpplvklwyqlekepivgaetfyvdgaanretklgkagyvtnrgrqkvvtltdttnqkt
elqaiylalqdsglevnivtdsqyalgiiqaqpdqseselvnqiieqlikkekvylawvp
ahkgiggneqvdklvsagirkvl

    Sequence, based on observed residues (ATOM records): (download) 
    >2ynhA (A:)
nspispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpynt
pvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsv
pldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdi
viyqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdk
wtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkaltevipltee
aelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmr
gahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvn
tpplvklwyqlekepivgaetfyvdgaanretklgkagyvtnrgrqkvvtltdttnqkte
lqaiylalqdsglevnivtdsqyalgiiqaqpdqseselvnqiieqlikkekvylawvpa
hkgiggneqvdklvsagirk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ynhB (B:)
maghhhhhhgsaenlyfqgpispietvpvklkpgmdgpkvkqwplteekikalveictem
ekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglk
kkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifq
ssmtkilepfrkqnpdiviyqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkh
qkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlck
llrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqi
yqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetw
wteywqatwipewefvntpplvklwyq

    Sequence, based on observed residues (ATOM records): (download) 
    >2ynhB (B:)
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedf
rkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqym
ddlyvgsdleigqhrtkieelrqhllrwgltwmgyelhpdkwtvqpivlpekdswtvndi
qklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgv
yydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyartndvkqlteavqkittesivi
wgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq