PDB entry 2yk1

View 2yk1 on RCSB PDB site
Description: Structure of human anti-nicotine Fab fragment in complex with nicotine
Class: immune system
Keywords: immune system, monoclonal antibodies, anti-smoking vaccine
Deposited on 2011-05-25, released 2011-11-16
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-01-18, with a file datestamp of 2012-01-13.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.22648
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Fab fragment, heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2YK1 (Start-210)
  • Chain 'L':
    Compound: Fab fragment, light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2YK1
    Domains in SCOPe 2.06: d2yk1l1, d2yk1l2
  • Heterogens: NCT, HOH

PDB Chain Sequences:

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >2yk1L (L:)
qseltqppsasgtpgqrvtiscsgsssnigsnyvywyqqlpgtapklliyrnnqrpsgvp
drfsgsksgtsaslaisglrsedeadyycaawddslsawvfgggtqldilgqpkaapsvt
lfppsseelqapkatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >2yk1L (L:)
eltqppsasgtpgqrvtiscsgsssnigsnyvywyqqlpgtapklliyrnnqrpsgvpdr
fsgsksgtsaslaisglrsedeadyycaawddslsawvfgggtqldilgqpkaapsvtlf
ppspkatlvclisdfypgavtvaagvetttpskqsnnkyaassylsltpeqwsyscqvth
egstvekt