PDB entry 2ye3

View 2ye3 on RCSB PDB site
Description: hsp90 inhibitors and drugs from fragment and virtual screening
Class: chaperone
Keywords: pu3, ATPase, chaperone, stress response, nucleotide-binding, ATP-binding, phosphoprotein, phosphorylation
Deposited on 2011-03-25, released 2011-06-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-06-29, with a file datestamp of 2011-06-24.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.17776
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heat shock protein HSP 90-alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ye3a_
  • Heterogens: VXX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ye3A (A:)
mghhhhhhhhhhssghiddadkhmdqpmeeeevetfafqaeiaqlmsliintfysnkeif
lrelisnssdaldkiryesltdpskldsgkelhinlipnkqdrtltivdtgigmtkadli
nnlgtiaksgtkafmealqagadismigqfgvgfysaylvaekvtvitkhnddeqyawes
saggsftvrtdtgepmgrgtkvilhlkedqteyleerrikeivkkhsqfigypitlfvek
erdkevsddeae

    Sequence, based on observed residues (ATOM records): (download) 
    >2ye3A (A:)
evetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskldsgke
lhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadismigqfg
vgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedqt
eyleerrikeivkkhsqfigypitlfvek