PDB entry 2xno

View 2xno on RCSB PDB site
Description: structure of nek2 bound to cct243779
Class: transferase
Keywords: transferase, centrosome, mitosis, cell cycle
Deposited on 2010-08-05, released 2011-03-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-03-30, with a file datestamp of 2011-03-25.
Experiment type: XRAY
Resolution: 1.98 Å
R-factor: 0.1725
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine/threonine-protein kinase nek2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51955 (Start-270)
      • expression tag (271-278)
    Domains in SCOPe 2.08: d2xnoa1, d2xnoa2
  • Heterogens: ED8, CL, EDO, GOL, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xnoA (A:)
mpsraedyevlytigtgsygrcqkirrksdgkilvwkeldygsmteaekqmlvsevnllr
elkhpnivryydriidrtnttlyivmeyceggdlasvitkgtkerqyldeefvlrvmtql
tlalkechrrsdgghtvlhrdlkpanvfldgkqnvklgdfglarilnhdtsfaktfvgtp
yymspeqmnrmsyneksdiwslgcllyelcalmppftafsqkelagkiregkfrripyry
sdelneiitrmlnlkdyhrpsveeilenplilehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2xnoA (A:)
sraedyevlytigtgsygrcqkirrksdgkilvwkeldygsmteaekqmlvsevnllrel
khpnivryydriidrtnttlyivmeyceggdlasvitkgtkerqyldeefvlrvmtqltl
alkechrrsrdlkpanvfldgkqnvklgdffvgtpyymspeqmnrneksdiwslgcllye
lcalmppftafsqkelagkiregkfrripyrysdelneiitrmlnlkdyhrpsveeilen
plilehhhhhh