PDB entry 2xk2
View 2xk2 on RCSB PDB site
Description: Structure of HSP90 with small molecule inhibitor bound
Class: chaperone
Keywords: chaperone, stress response
Deposited on
2010-07-07, released
2010-09-01
The last revision prior to the SCOPe 2.08 freeze date was dated
2013-04-24, with a file datestamp of
2013-04-19.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.1888
AEROSPACI score: 0.45
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Heat shock protein HSP 90-alpha
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2xk2a_ - Heterogens: MG, ADP, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2xk2A (A:)
mgsshhhhhhssglvprgshmdqpmeeeevetfafqaeiaqlmsliintfysnkeiflre
lisnssdaldkiryesltdpskldsgkelhinlipnkqdrtltivdtgigmtkadlinnl
gtiaksgtkafmealqagadismigqfgvgfysaylvaekvtvitkhnddeqyawessag
gsftvrtdtgepmgrgtkvilhlkedqteyleerrikeivkkhsqfigypitlfvekerd
kevsddeae
Sequence, based on observed residues (ATOM records): (download)
>2xk2A (A:)
meeeevetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskld
sgkelhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadismi
gqfgvgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlk
edqteyleerrikeivkkhsqfigypitlfvek