PDB entry 2xhd

View 2xhd on RCSB PDB site
Description: crystal structure of n-((2s)-5-(6-fluoro-3-pyridinyl)-2,3-dihydro-1h-inden-2-yl)-2-propanesulfonamide in complex with the ligand binding domain of the human glua2 receptor
Class: transport protein
Keywords: transport protein, ion channel
Deposited on 2010-06-14, released 2010-07-21
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-06-01, with a file datestamp of 2011-05-27.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.202
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P42262 (119-262)
      • variant (241)
    • PDB 2XHD (117-118)
    Domains in SCOPe 2.02: d2xhda_
  • Chain 'B':
    Compound: Glutamate receptor 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P42262 (119-End)
      • variant (241)
    • PDB 2XHD (117-118)
    Domains in SCOPe 2.02: d2xhdb_
  • Heterogens: GLU, 7T9, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xhdA (A:)
ganktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgk
ygardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtp
iesaedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvar
vrkskgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslrtpvnlavlk
lseqgvldklknkwwydkgecga

    Sequence, based on observed residues (ATOM records): (download) 
    >2xhdA (A:)
nktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyg
ardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpie
saedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvr
kskgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslrtpvnlavlkls
eqgvldklknkwwydkgecga

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2xhdB (B:)
ganktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgk
ygardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtp
iesaedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvar
vrkskgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslrtpvnlavlk
lseqgvldklknkwwydkgecga

    Sequence, based on observed residues (ATOM records): (download) 
    >2xhdB (B:)
ktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyga
rdadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpies
aedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrk
skgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslrtpvnlavlklse
qgvldklknkwwydcg