SCOPe 2.04: Structural Classification of Proteins

PDB entry 2xh0

View 2xh0 on RCSB PDB site
Description: engineering the enolase active site pocket: crystal structure of the s39n q167k d321r mutant of yeast enolase 1
Class: lyase
Keywords: enolase superfamiliy, lyase, tim-barrel, glycolysis, metal-binding, gluconeogenesis
Deposited on 2010-06-08, released 2010-08-25
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-04-20, with a file datestamp of 2011-04-15.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.199
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: enolase 1
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P00924 (0-435)
  - expression tag (436-437)
  - engineered mutation (38)
  - engineered mutation (166)
  - conflict (240)
  - engineered mutation (320)
Domains in SCOPe 2.04: d2xh0a1, d2xh0a2
Chain 'B':
Compound: enolase 1
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P00924 (0-435)
  - expression tag (436-437)
  - engineered mutation (38)
  - engineered mutation (166)
  - conflict (240)
  - engineered mutation (320)
Domains in SCOPe 2.04: d2xh0b1, d2xh0b2
Chain 'C':
Compound: enolase 1
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P00924 (0-435)
  - expression tag (436-437)
  - engineered mutation (38)
  - engineered mutation (166)
  - conflict (240)
  - engineered mutation (320)
Domains in SCOPe 2.04: d2xh0c1, d2xh0c2
Chain 'D':
Compound: enolase 1
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P00924 (0-435)
  - expression tag (436-437)
  - engineered mutation (38)
  - engineered mutation (166)
  - conflict (240)
  - engineered mutation (320)
Domains in SCOPe 2.04: d2xh0d1, d2xh0d2
Heterogens: MG, PEP, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2xh0A (A:)
avskvyarsvydsrgnptvevelttekgvfrsivpsgantgvhealemrdgdkskwmgkg
vlhavknvndviapafvkanidvkdqkavddflisldgtanksklganailgvslaasra
aaaeknvplykhladlsksktspyvlpvpflnvlnggshaggalalkefmiaptgaktfa
ealrigsevyhnlksltkkrygasagnvgdeggvapniqtaeealdlivdaikaaghdgk
ikigldcasseffkdgkydldfknpnsdkskwltgpqladlyhslmkrypivsiedpfae
ddweawshffktagiqivadrltvtnpkriataiekkaadalllkvnqigtlsesikaaq
dsfaagwgvmvshrsgetedtfiadlvvglrtgqiktgaparserlaklnqllrieeelg
dnavfagenfhhgdkllhhhhhh

Sequence, based on observed residues (ATOM records): (download)

>2xh0A (A:)
avskvyarsvydsrgnptvevelttekgvfrsivpsgantgvhealemrdgdkskwmgkg
vlhavknvndviapafvkanidvkdqkavddflisldgtanksklganailgvslaasra
aaaeknvplykhladlsksktspyvlpvpflnvlnggshaggalalkefmiaptgaktfa
ealrigsevyhnlksltkkrygasagnvgdeggvapniqtaeealdlivdaikaaghdgk
ikigldcasseffkdgkydldfknpnsdkskwltgpqladlyhslmkrypivsiedpfae
ddweawshffktagiqivadrltvtnpkriataiekkaadalllkvnqigtlsesikaaq
dsfaagwgvmvshrsgetedtfiadlvvglrtgqiktgaparserlaklnqllrieeelg
dnavfagenfhhgdkllh

Chain 'B':
Sequence, based on SEQRES records: (download)

>2xh0B (B:)
avskvyarsvydsrgnptvevelttekgvfrsivpsgantgvhealemrdgdkskwmgkg
vlhavknvndviapafvkanidvkdqkavddflisldgtanksklganailgvslaasra
aaaeknvplykhladlsksktspyvlpvpflnvlnggshaggalalkefmiaptgaktfa
ealrigsevyhnlksltkkrygasagnvgdeggvapniqtaeealdlivdaikaaghdgk
ikigldcasseffkdgkydldfknpnsdkskwltgpqladlyhslmkrypivsiedpfae
ddweawshffktagiqivadrltvtnpkriataiekkaadalllkvnqigtlsesikaaq
dsfaagwgvmvshrsgetedtfiadlvvglrtgqiktgaparserlaklnqllrieeelg
dnavfagenfhhgdkllhhhhhh

Sequence, based on observed residues (ATOM records): (download)

>2xh0B (B:)
avskvyarsvydsrgnptvevelttekgvfrsivpsgantgvhealemrdgdkskwmgkg
vlhavknvndviapafvkanidvkdqkavddflisldgtanksklganailgvslaasra
aaaeknvplykhladlsksktspyvlpvpflnvlnggshaggalalkefmiaptgaktfa
ealrigsevyhnlksltkkrygasagnvgdeggvapniqtaeealdlivdaikaaghdgk
ikigldcasseffkdgkydldfknpnsdkskwltgpqladlyhslmkrypivsiedpfae
ddweawshffktagiqivadrltvtnpkriataiekkaadalllkvnqigtlsesikaaq
dsfaagwgvmvshrsgetedtfiadlvvglrtgqiktgaparserlaklnqllrieeelg
dnavfagenfhhgdkllh

Chain 'C':
Sequence, based on SEQRES records: (download)

>2xh0C (C:)
avskvyarsvydsrgnptvevelttekgvfrsivpsgantgvhealemrdgdkskwmgkg
vlhavknvndviapafvkanidvkdqkavddflisldgtanksklganailgvslaasra
aaaeknvplykhladlsksktspyvlpvpflnvlnggshaggalalkefmiaptgaktfa
ealrigsevyhnlksltkkrygasagnvgdeggvapniqtaeealdlivdaikaaghdgk
ikigldcasseffkdgkydldfknpnsdkskwltgpqladlyhslmkrypivsiedpfae
ddweawshffktagiqivadrltvtnpkriataiekkaadalllkvnqigtlsesikaaq
dsfaagwgvmvshrsgetedtfiadlvvglrtgqiktgaparserlaklnqllrieeelg
dnavfagenfhhgdkllhhhhhh

Sequence, based on observed residues (ATOM records): (download)

>2xh0C (C:)
avskvyarsvydsrgnptvevelttekgvfrsivpsgantgvhealemrdgdkskwmgkg
vlhavknvndviapafvkanidvkdqkavddflisldgtanksklganailgvslaasra
aaaeknvplykhladlsksktspyvlpvpflnvlnggshaggalalkefmiaptgaktfa
ealrigsevyhnlksltkkrygasagnvgdeggvapniqtaeealdlivdaikaaghdgk
ikigldcasseffkdgkydldfknpnsdkskwltgpqladlyhslmkrypivsiedpfae
ddweawshffktagiqivadrltvtnpkriataiekkaadalllkvnqigtlsesikaaq
dsfaagwgvmvshrsgetedtfiadlvvglrtgqiktgaparserlaklnqllrieeelg
dnavfagenfhhgdkllh

Chain 'D':
Sequence, based on SEQRES records: (download)

>2xh0D (D:)
avskvyarsvydsrgnptvevelttekgvfrsivpsgantgvhealemrdgdkskwmgkg
vlhavknvndviapafvkanidvkdqkavddflisldgtanksklganailgvslaasra
aaaeknvplykhladlsksktspyvlpvpflnvlnggshaggalalkefmiaptgaktfa
ealrigsevyhnlksltkkrygasagnvgdeggvapniqtaeealdlivdaikaaghdgk
ikigldcasseffkdgkydldfknpnsdkskwltgpqladlyhslmkrypivsiedpfae
ddweawshffktagiqivadrltvtnpkriataiekkaadalllkvnqigtlsesikaaq
dsfaagwgvmvshrsgetedtfiadlvvglrtgqiktgaparserlaklnqllrieeelg
dnavfagenfhhgdkllhhhhhh

Sequence, based on observed residues (ATOM records): (download)

>2xh0D (D:)
avskvyarsvydsrgnptvevelttekgvfrsivpsgantgvhealemrdgdkskwmgkg
vlhavknvndviapafvkanidvkdqkavddflisldgtanksklganailgvslaasra
aaaeknvplykhladlsksktspyvlpvpflnvlnggshaggalalkefmiaptgaktfa
ealrigsevyhnlksltkkrygasagnvgdeggvapniqtaeealdlivdaikaaghdgk
ikigldcasseffkdgkydldfknpnsdkskwltgpqladlyhslmkrypivsiedpfae
ddweawshffktagiqivadrltvtnpkriataiekkaadalllkvnqigtlsesikaaq
dsfaagwgvmvshrsgetedtfiadlvvglrtgqiktgaparserlaklnqllrieeelg
dnavfagenfhhgdkllh