PDB entry 2xez

View 2xez on RCSB PDB site
Description: crystal structure of checkpoint kinase 1 (chk1) in complex with inhibitors
Class: transferase
Keywords: transferase, DNA repair, cell cycle
Deposited on 2010-05-19, released 2010-07-07
The last revision prior to the SCOPe 2.02 freeze date was dated 2010-07-21, with a file datestamp of 2010-07-16.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.2114
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase Chk1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d2xeza_
  • Heterogens: XEZ, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xezA (A:)
mavpfvedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicink
mlnhenvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvy
lhgigithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellk
rrefhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsapla
llhkilvenpsaritipdikkdrwynkplkkgakrprvtsggvsespsg

    Sequence, based on observed residues (ATOM records): (download) 
    >2xezA (A:)
edwdlvqtlgevqlavnrvteeavavkivdmnikkeicinkmlnhenvvkfyghrreiqy
lfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigithrdikpenlllder
dnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaepvdvwscgivltam
lagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilvenpsaritipdikk
drwynkplk