SCOPe 2.08: Structural Classification of Proteins

PDB entry 2x6t

View 2x6t on RCSB PDB site
Description: AGME bound to ADP-B-mannose
Class: isomerase
Keywords: isomerase, carbohydrate metabolism, stress response
Deposited on 2010-02-21, released 2010-03-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.36 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: ADP-l-glycero-d-manno-heptose-6-epimerase
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
- PDB 2X6T
  - engineered mutation (186)
- Uniprot P67911 (47-End)
Domains in SCOPe 2.08: d2x6ta_
Chain 'B':
Compound: ADP-l-glycero-d-manno-heptose-6-epimerase
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
- PDB 2X6T
  - engineered mutation (186)
- Uniprot P67911 (47-End)
Domains in SCOPe 2.08: d2x6tb_
Chain 'C':
Compound: ADP-l-glycero-d-manno-heptose-6-epimerase
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
- PDB 2X6T
  - engineered mutation (186)
- Uniprot P67911 (47-End)
Domains in SCOPe 2.08: d2x6tc_
Chain 'D':
Compound: ADP-l-glycero-d-manno-heptose-6-epimerase
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
- PDB 2X6T
  - engineered mutation (186)
- Uniprot P67911 (47-End)
Domains in SCOPe 2.08: d2x6td_
Chain 'E':
Compound: ADP-l-glycero-d-manno-heptose-6-epimerase
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
- PDB 2X6T
  - engineered mutation (186)
- Uniprot P67911 (47-End)
Domains in SCOPe 2.08: d2x6te_
Chain 'F':
Compound: ADP-l-glycero-d-manno-heptose-6-epimerase
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
- PDB 2X6T
  - engineered mutation (186)
- Uniprot P67911 (47-End)
Domains in SCOPe 2.08: d2x6tf_
Chain 'G':
Compound: ADP-l-glycero-d-manno-heptose-6-epimerase
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
- PDB 2X6T
  - engineered mutation (186)
- Uniprot P67911 (47-End)
Domains in SCOPe 2.08: d2x6tg_
Chain 'H':
Compound: ADP-l-glycero-d-manno-heptose-6-epimerase
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
- PDB 2X6T
  - engineered mutation (186)
- Uniprot P67911 (47-End)
Domains in SCOPe 2.08: d2x6th_
Chain 'I':
Compound: ADP-l-glycero-d-manno-heptose-6-epimerase
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
- PDB 2X6T
  - engineered mutation (186)
- Uniprot P67911 (47-End)
Domains in SCOPe 2.08: d2x6ti_
Chain 'J':
Compound: ADP-l-glycero-d-manno-heptose-6-epimerase
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
- PDB 2X6T
  - engineered mutation (186)
- Uniprot P67911 (47-End)
Domains in SCOPe 2.08: d2x6tj_
Heterogens: NAP, GOL, ADP, BMA, CL, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2x6tA (A:)
mhhhhhhssglvprgsgmketaaakferqhmdspdlgtgggsgiegrmiivtggagfigs
nivkalndkgitdilvvdnlkdgtkfvnlvdlniadymdkedfliqimageefgdveaif
hegacssttewdgkymmdnnyqyskellhyclereipflyassaatyggrtsdfiesrey
ekplnvfgyskflfdeyvrqilpeansqivgfryfnvygpreghkgsmasvafhlntqln
ngespklfegsenfkrdfvyvgdvadvnlwflengvsgifnlgtgraesfqavadatlay
hkkgqieyipfpdklkgryqaftqadltnlraagydkpfktvaegvteymawlnrda