PDB entry 2x4t

View 2x4t on RCSB PDB site
Description: crystal structure of MHC class I hla-a2.1 bound to a peiodate-cleavable peptide
Class: immune system
Keywords: MHC class I, immunoglobulin domain, host-virus interaction, glycation, amyloidosis, amyloid, photocleavable peptide, immune response, immune system
Deposited on 2010-02-02, released 2010-03-02
The last revision prior to the SCOPe 2.02 freeze date was dated 2010-03-02, with a file datestamp of 2010-02-26.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.1858
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class I histocompatibility antigen, a-2.1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2X4T (0-0)
    • Uniprot P61769 (1-99)
    Domains in SCOPe 2.02: d2x4tb_
  • Chain 'C':
    Compound: 65 kda phosphoprotein
    Species: HUMAN HERPESVIRUS 5, synthetic [TaxId:10359]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06725 (0-8)
      • see remark 999 (3)
  • Chain 'D':
    Compound: hla class I histocompatibility antigen, a-2.1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2X4T (0-0)
    • Uniprot P61769 (1-99)
    Domains in SCOPe 2.02: d2x4te_
  • Chain 'F':
    Compound: 65 kda phosphoprotein
    Species: HUMAN HERPESVIRUS 5, synthetic [TaxId:10359]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06725 (0-8)
      • see remark 999 (3)
  • Heterogens: GOL, MES, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2x4tB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2x4tE (E:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'F':
    No sequence available.