PDB entry 2x4s

View 2x4s on RCSB PDB site
Description: crystal structure of MHC class I hla-a2.1 bound to a peptide representing the epitope of the h5n1 (avian flu) nucleoprotein
Class: immune system
Keywords: photocleavable peptide, glycoprotein, immune system, immunoglobulin domain, matrix (m1)
Deposited on 2010-02-02, released 2010-03-02
The last revision prior to the SCOPe 2.01 freeze date was dated 2010-03-02, with a file datestamp of 2010-02-26.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: 0.1818
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class I histocompatibility antigen, a-2.1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2X4S (0-0)
    • Uniprot P61769 (1-99)
    Domains in SCOPe 2.01: d2x4sb_
  • Chain 'C':
    Compound: h5n1 influenza a nucleoprotein
    Species: INFLUENZA VIRUS TYPE A, synthetic [TaxId:11320]
    Database cross-references and differences (RAF-indexed):
    • PDB 2X4S (0-8)
  • Chain 'D':
    Compound: hla class I histocompatibility antigen, a-2.1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2X4S (0-0)
    • Uniprot P61769 (1-99)
    Domains in SCOPe 2.01: d2x4se_
  • Chain 'F':
    Compound: h5n1 influenza a nucleoprotein
    Species: INFLUENZA VIRUS TYPE A, synthetic [TaxId:11320]
    Database cross-references and differences (RAF-indexed):
    • PDB 2X4S (0-8)
  • Heterogens: GOL, MES, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2x4sB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2x4sE (E:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'F':
    No sequence available.