PDB entry 2x0y

View 2x0y on RCSB PDB site
Description: screening-based discovery of drug-like o-glcnacase inhibitor scaffolds
Class: hydrolase
Keywords: glycosidase, hydrolase, cell adhesion
Deposited on 2009-12-18, released 2010-01-12
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-06-08, with a file datestamp of 2011-06-03.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.20433
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: O-GlcNAcase nagJ
    Species: Clostridium perfringens [TaxId:1502]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2x0ya1, d2x0ya2, d2x0ya3
  • Chain 'B':
    Compound: O-GlcNAcase nagJ
    Species: Clostridium perfringens [TaxId:1502]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2x0yb1, d2x0yb2, d2x0yb3
  • Heterogens: X0T, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2x0yA (A:)
vgpktgeenqvlvpnlnptpenlevvgdgfkitssinlvgeeeadenavnalrefltann
ieinsendpnsttliigevdddipeldealngttaenlkeegyalvsndgkiaiegkdgd
gtfygvqtfkqlvkesnipevnitdyptvsargivegfygtpwthqdrldqikfygenkl
ntyiyapkddpyhrekwrepypesemqrmqelinasaenkvdfvfgispgidirfdgdag
eedfnhlitkaeslydmgvrsfaiywddiqdksaakhaqvlnrfneefvkakgdvkplit
vpteydtgamvsngqpraytrifaetvdpsievmwtgpgvvtneiplsdaqlisgiynrn
mavwwnypvtdyfkgklalgpmhgldkglnqyvdfftvnpmehaelskisihtaadyswn
mdnydydkawnraidmlygdlaedmkvfanhstrmdnktwaksgredapelrakmdelwn
klsskedasalieelygefarmeeacnnlkanlpevaleecsrqldelitlaqgdkasld
mivaqlnedteayesakeiaqnklntalssfavisekvaqsfiqealsfdltli

    Sequence, based on observed residues (ATOM records): (download) 
    >2x0yA (A:)
vlvpnlnptpenlevvgdgfkitssinlvgeeeadenavnalrefltannieinsendpn
sttliigevdddipeldealngttaenlkeegyalvsndgkiaiegkdgdgtfygvqtfk
qlvkesnipevnitdyptvsargivegfygtpwthqdrldqikfygenklntyiyapkdd
pyhrekwrepypesemqrmqelinasaenkvdfvfgispgidirfdgdageedfnhlitk
aeslydmgvrsfaiywddiqdksaakhaqvlnrfneefvkakgdvkplitvpteydtgam
vsngqpraytrifaetvdpsievmwtgpgvvtneiplsdaqlisgiynrnmavwwnypvt
dyfkgklalgpmhgldkglnqyvdfftvnpmehaelskisihtaadyswnmdnydydkaw
nraidmlygdlaedmkvfanhstrmdnktwaksgredapelrakmdelwnklsskedasa
lieelygefarmeeacnnlkanlpevaleecsrqldelitlaqgdkasldmivaqlnedt
eayesakeiaqnklntalssfavisekvaqsfiqealsfdltli

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2x0yB (B:)
vgpktgeenqvlvpnlnptpenlevvgdgfkitssinlvgeeeadenavnalrefltann
ieinsendpnsttliigevdddipeldealngttaenlkeegyalvsndgkiaiegkdgd
gtfygvqtfkqlvkesnipevnitdyptvsargivegfygtpwthqdrldqikfygenkl
ntyiyapkddpyhrekwrepypesemqrmqelinasaenkvdfvfgispgidirfdgdag
eedfnhlitkaeslydmgvrsfaiywddiqdksaakhaqvlnrfneefvkakgdvkplit
vpteydtgamvsngqpraytrifaetvdpsievmwtgpgvvtneiplsdaqlisgiynrn
mavwwnypvtdyfkgklalgpmhgldkglnqyvdfftvnpmehaelskisihtaadyswn
mdnydydkawnraidmlygdlaedmkvfanhstrmdnktwaksgredapelrakmdelwn
klsskedasalieelygefarmeeacnnlkanlpevaleecsrqldelitlaqgdkasld
mivaqlnedteayesakeiaqnklntalssfavisekvaqsfiqealsfdltli

    Sequence, based on observed residues (ATOM records): (download) 
    >2x0yB (B:)
qvlvpnlnptpenlevvgdgfkitssinlvgeeeadenavnalrefltannieinsendp
nsttliigevdddipeldealngttaenlkeegyalvsndgkiaiegkdgdgtfygvqtf
kqlvkesnipevnitdyptvsargivegfygtpwthqdrldqikfygenklntyiyapkd
dpyhrekwrepypesemqrmqelinasaenkvdfvfgispgidirfdgdageedfnhlit
kaeslydmgvrsfaiywddiqdksaakhaqvlnrfneefvkakgdvkplitvpteydtga
mvsngqpraytrifaetvdpsievmwtgpgvvtneiplsdaqlisgiynrnmavwwnypv
tdyfkgklalgpmhgldkglnqyvdfftvnpmehaelskisihtaadyswnmdnydydka
wnraidmlygdlaedmkvfanhstrmdnktwaksgredapelrakmdelwnklsskedas
alieelygefarmeeacnnlkanlpevaleecsrqldelitlaqgdkasldmivaqlned
teayesakeiaqnklntalssfavisekvaqsfiqealsfdltli