PDB entry 2wva

View 2wva on RCSB PDB site
Description: structural insights into the pre-reaction state of pyruvate decarboxylase from zymomonas mobilis
Class: lyase
Keywords: thiamin diphosphate, lyase, flavoprotein, metal-binding, alcohol fermentation
Deposited on 2009-10-15, released 2010-02-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-10-19, with a file datestamp of 2011-10-14.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.195
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2wvaa1, d2wvaa2, d2wvaa3
  • Chain 'B':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2wvab1, d2wvab2, d2wvab3
  • Chain 'E':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2wvae1, d2wvae2, d2wvae3
  • Chain 'F':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2wvaf1, d2wvaf2, d2wvaf3
  • Chain 'V':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2wvav1, d2wvav2, d2wvav3
  • Chain 'X':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2wvax1, d2wvax2, d2wvax3
  • Chain 'Y':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2wvay1, d2wvay2, d2wvay3
  • Chain 'Z':
    Compound: pyruvate decarboxylase
    Species: Zymomonas mobilis [TaxId:542]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2wvaz1, d2wvaz2, d2wvaz3
  • Heterogens: TPU, MG, PYR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wvaA (A:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >2wvaA (A:)
sytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegya
rakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktdy
hyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgpa
salfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggava
tmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipdp
kklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapadp
saplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvpa
afgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgpy
nniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfigr
edcteelvkwgkrvaaansrkpvnk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2wvaB (B:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >2wvaB (B:)
sytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegya
rakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktdy
hyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgpa
salfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggava
tmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipdp
kklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapadp
saplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvpa
afgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgpy
nniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfigr
edcteelvkwgkrvaaansrkpvnk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2wvaE (E:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >2wvaE (E:)
sytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegya
rakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktdy
hyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgpa
salfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggava
tmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipdp
kklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapadp
saplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvpa
afgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgpy
nniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfigr
edcteelvkwgkrvaaansrkpvnk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2wvaF (F:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >2wvaF (F:)
sytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegya
rakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktdy
hyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgpa
salfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggava
tmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipdp
kklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapadp
saplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvpa
afgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgpy
nniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfigr
edcteelvkwgkrvaaansrkpvnk

  • Chain 'V':
    Sequence, based on SEQRES records: (download) 
    >2wvaV (V:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >2wvaV (V:)
sytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegya
rakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktdy
hyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgpa
salfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggava
tmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipdp
kklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapadp
saplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvpa
afgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgpy
nniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfigr
edcteelvkwgkrvaaansrkpvnk

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >2wvaX (X:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >2wvaX (X:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnk

  • Chain 'Y':
    Sequence, based on SEQRES records: (download) 
    >2wvaY (Y:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >2wvaY (Y:)
sytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegya
rakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktdy
hyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgpa
salfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggava
tmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipdp
kklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapadp
saplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvpa
afgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgpy
nniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfigr
edcteelvkwgkrvaaansrkpvnk

  • Chain 'Z':
    Sequence, based on SEQRES records: (download) 
    >2wvaZ (Z:)
msytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegy
arakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktd
yhyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgp
asalfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggav
atmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipd
pkklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapad
psaplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvp
aafgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgp
ynniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfig
redcteelvkwgkrvaaansrkpvnkll

    Sequence, based on observed residues (ATOM records): (download) 
    >2wvaZ (Z:)
sytvgtylaerlvqiglkhhfavagdynlvlldnlllnknmeqvyccnelncgfsaegya
rakgaaaavvtysvgalsafdaiggayaenlpvilisgapnnndhaaghvlhhalgktdy
hyqlemaknitaaaeaiytpeeapakidhviktalrekkpvyleiacniasmpcaapgpa
salfndeasdeaslnaaveetlkfianrdkvavlvgsklraagaeeaavkfadalggava
tmaaaksffpeenphyigtswgevsypgvektmkeadavialapvfndysttgwtdipdp
kklvlaeprsvvvngirfpsvhlkdyltrlaqkvskktgaldffkslnagelkkaapadp
saplvnaeiarqvealltpnttviaetgdswfnaqrmklpngarveyemqwghigwsvpa
afgyavgaperrnilmvgdgsfqltaqevaqmvrlklpviiflinnygytievmihdgpy
nniknwdyaglmevfngnggydsgagkglkaktggelaeaikvalantdgptliecfigr
edcteelvkwgkrvaaansrkpvnk