PDB entry 2wu5

View 2wu5 on RCSB PDB site
Description: crystal structure of the e. coli succinate:quinone oxidoreductase (sqr) sdhd his71met mutant
Class: oxidoreductase
Keywords: cell inner membrane, tricarboxylic acid cycle, metal-binding, transmembrane, transport, flavoprotein, oxidoreductase, electron transport
Deposited on 2009-09-29, released 2010-08-25
The last revision prior to the SCOPe 2.04 freeze date was dated 2010-08-25, with a file datestamp of 2010-08-20.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.2153
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Succinate dehydrogenase flavoprotein subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2wu5a1, d2wu5a2, d2wu5a3
  • Chain 'B':
    Compound: succinate dehydrogenase iron-sulfur subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2wu5b1, d2wu5b2
  • Chain 'C':
    Compound: succinate dehydrogenase cytochrome b556 subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2wu5c_
  • Chain 'D':
    Compound: succinate dehydrogenase hydrophobic membrane anchor protein subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0AC44 (Start-114)
      • engineered mutation (70)
  • Chain 'E':
    Compound: Succinate dehydrogenase flavoprotein subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2wu5e1, d2wu5e2, d2wu5e3
  • Chain 'F':
    Compound: succinate dehydrogenase iron-sulfur subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2wu5f1, d2wu5f2
  • Chain 'G':
    Compound: succinate dehydrogenase cytochrome b556 subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2wu5g_
  • Chain 'H':
    Compound: succinate dehydrogenase hydrophobic membrane anchor protein subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0AC44 (Start-114)
      • engineered mutation (70)
  • Chain 'I':
    Compound: Succinate dehydrogenase flavoprotein subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2wu5i1, d2wu5i2, d2wu5i3
  • Chain 'J':
    Compound: succinate dehydrogenase iron-sulfur subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2wu5j1, d2wu5j2
  • Chain 'K':
    Compound: succinate dehydrogenase cytochrome b556 subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2wu5k_
  • Chain 'L':
    Compound: succinate dehydrogenase hydrophobic membrane anchor protein subunit
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0AC44 (Start-114)
      • engineered mutation (70)
  • Heterogens: FAD, TEO, NA, FES, SF4, F3S, HEM, CBE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2wu5A (A:)
mklpvrefdavvigaggagmraalqisqsgqtcallskvfptrshtvsaqggitvalgnt
hednwewhmydtvkgsdyigdqdaieymcktgpeailelehmglpfsrlddgriyqrpfg
gqsknfggeqaartaaaadrtghallhtlyqqnlknhttifsewyaldlvknqdgavvgc
talcietgevvyfkaratvlatggagriyqsttnahintgdgvgmairagvpvqdmemwq
fhptgiagagvlvtegcrgeggyllnkhgerfmeryapnakdlagrdvvarsimieireg
rgcdgpwgphaklkldhlgkevlesrlpgilelsrtfahvdpvkepipviptchymmggi
ptkvtgqaltvnekgedvvvpglfavgeiacvsvhganrlggnslldlvvfgraaglhlq
esiaeqgalrdasesdveasldrlnrwnnnrngedpvairkalqecmqhnfsvfregdam
akgleqlkvirerlknarlddtssefntqrvecleldnlmetayatavsanfrtesrgah
srfdfpdrddenwlchslylpesesmtrrsvnmepklrpafppkirty

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2wu5B (B:)
mrlefsiyrynpdvddaprmqdytleadegrdmmlldaliqlkekdpslsfrrscregvc
gsdglnmngknglacitpisalnqpgkkivirplpglpvirdlvvdmgqfyaqyekikpy
llnngqnpparehlqmpeqrekldglyecilcaccstscpsfwwnpdkfigpagllaayr
flidsrdtetdsrldglsdafsvfrchsimncvsvcpkglnptraighiksmllqrna

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2wu5C (C:)
mirnvkkqrpvnldlqtirfpitaiasilhrvsgvitfvavgillwllgtslsspegfeq
asaimgsffvkfimwgiltalayhvvvgirhmmmdfgyleetfeagkrsakisfvitvvl
sllagvlvw

    Sequence, based on observed residues (ATOM records): (download) 
    >2wu5C (C:)
qrpvnldlqtirfpitaiasilhrvsgvitfvavgillwllgtslsspegfeqasaimgs
ffvkfimwgiltalayhvvvgirhmmmdfgyleetfeagkrsakisfvitvvlsllagvl
vw

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2wu5E (E:)
mklpvrefdavvigaggagmraalqisqsgqtcallskvfptrshtvsaqggitvalgnt
hednwewhmydtvkgsdyigdqdaieymcktgpeailelehmglpfsrlddgriyqrpfg
gqsknfggeqaartaaaadrtghallhtlyqqnlknhttifsewyaldlvknqdgavvgc
talcietgevvyfkaratvlatggagriyqsttnahintgdgvgmairagvpvqdmemwq
fhptgiagagvlvtegcrgeggyllnkhgerfmeryapnakdlagrdvvarsimieireg
rgcdgpwgphaklkldhlgkevlesrlpgilelsrtfahvdpvkepipviptchymmggi
ptkvtgqaltvnekgedvvvpglfavgeiacvsvhganrlggnslldlvvfgraaglhlq
esiaeqgalrdasesdveasldrlnrwnnnrngedpvairkalqecmqhnfsvfregdam
akgleqlkvirerlknarlddtssefntqrvecleldnlmetayatavsanfrtesrgah
srfdfpdrddenwlchslylpesesmtrrsvnmepklrpafppkirty

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2wu5F (F:)
mrlefsiyrynpdvddaprmqdytleadegrdmmlldaliqlkekdpslsfrrscregvc
gsdglnmngknglacitpisalnqpgkkivirplpglpvirdlvvdmgqfyaqyekikpy
llnngqnpparehlqmpeqrekldglyecilcaccstscpsfwwnpdkfigpagllaayr
flidsrdtetdsrldglsdafsvfrchsimncvsvcpkglnptraighiksmllqrna

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2wu5G (G:)
mirnvkkqrpvnldlqtirfpitaiasilhrvsgvitfvavgillwllgtslsspegfeq
asaimgsffvkfimwgiltalayhvvvgirhmmmdfgyleetfeagkrsakisfvitvvl
sllagvlvw

    Sequence, based on observed residues (ATOM records): (download) 
    >2wu5G (G:)
qrpvnldlqtirfpitaiasilhrvsgvitfvavgillwllgtslsspegfeqasaimgs
ffvkfimwgiltalayhvvvgirhmmmdfgyleetfeagkrsakisfvitvvlsllagvl
vw

  • Chain 'H':
    No sequence available.

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2wu5I (I:)
mklpvrefdavvigaggagmraalqisqsgqtcallskvfptrshtvsaqggitvalgnt
hednwewhmydtvkgsdyigdqdaieymcktgpeailelehmglpfsrlddgriyqrpfg
gqsknfggeqaartaaaadrtghallhtlyqqnlknhttifsewyaldlvknqdgavvgc
talcietgevvyfkaratvlatggagriyqsttnahintgdgvgmairagvpvqdmemwq
fhptgiagagvlvtegcrgeggyllnkhgerfmeryapnakdlagrdvvarsimieireg
rgcdgpwgphaklkldhlgkevlesrlpgilelsrtfahvdpvkepipviptchymmggi
ptkvtgqaltvnekgedvvvpglfavgeiacvsvhganrlggnslldlvvfgraaglhlq
esiaeqgalrdasesdveasldrlnrwnnnrngedpvairkalqecmqhnfsvfregdam
akgleqlkvirerlknarlddtssefntqrvecleldnlmetayatavsanfrtesrgah
srfdfpdrddenwlchslylpesesmtrrsvnmepklrpafppkirty

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2wu5J (J:)
mrlefsiyrynpdvddaprmqdytleadegrdmmlldaliqlkekdpslsfrrscregvc
gsdglnmngknglacitpisalnqpgkkivirplpglpvirdlvvdmgqfyaqyekikpy
llnngqnpparehlqmpeqrekldglyecilcaccstscpsfwwnpdkfigpagllaayr
flidsrdtetdsrldglsdafsvfrchsimncvsvcpkglnptraighiksmllqrna

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >2wu5K (K:)
mirnvkkqrpvnldlqtirfpitaiasilhrvsgvitfvavgillwllgtslsspegfeq
asaimgsffvkfimwgiltalayhvvvgirhmmmdfgyleetfeagkrsakisfvitvvl
sllagvlvw

    Sequence, based on observed residues (ATOM records): (download) 
    >2wu5K (K:)
qrpvnldlqtirfpitaiasilhrvsgvitfvavgillwllgtslsspegfeqasaimgs
ffvkfimwgiltalayhvvvgirhmmmdfgyleetfeagkrsakisfvitvvlsllagvl
vw

  • Chain 'L':
    No sequence available.