PDB entry 2wl6

View 2wl6 on RCSB PDB site
Description: biosynthetic thiolase from z. ramigera. the n316h-h348n mutant.
Class: transferase
Keywords: acyltransferase, phb biosynthesis, cytoplasm, transferase, thiolase fold
Deposited on 2009-06-22, released 2009-11-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-08-09, with a file datestamp of 2017-08-04.
Experiment type: XRAY
Resolution: 2.98 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acetyl-CoA acetyltransferase
    Species: ZOOGLOEA RAMIGERA [TaxId:350]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07097 (11-391)
      • see remark 999 (128)
      • engineered mutation (315)
      • engineered mutation (347)
    • PDB 2WL6 (10-10)
    Domains in SCOPe 2.08: d2wl6a1, d2wl6a2
  • Chain 'B':
    Compound: Acetyl-CoA acetyltransferase
    Species: ZOOGLOEA RAMIGERA [TaxId:350]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07097 (11-391)
      • see remark 999 (128)
      • engineered mutation (315)
      • engineered mutation (347)
    • PDB 2WL6 (10-10)
    Domains in SCOPe 2.08: d2wl6b1
  • Chain 'C':
    Compound: Acetyl-CoA acetyltransferase
    Species: ZOOGLOEA RAMIGERA [TaxId:350]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07097 (11-391)
      • see remark 999 (128)
      • engineered mutation (315)
      • engineered mutation (347)
    • PDB 2WL6 (10-10)
    Domains in SCOPe 2.08: d2wl6c1
  • Chain 'D':
    Compound: Acetyl-CoA acetyltransferase
    Species: ZOOGLOEA RAMIGERA [TaxId:350]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07097 (11-391)
      • see remark 999 (128)
      • engineered mutation (315)
      • engineered mutation (347)
    • PDB 2WL6 (10-10)
    Domains in SCOPe 2.08: d2wl6d1
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wl6A (A:)
stpsiviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpa
gegqnparqaamkagvpqeatawgmnqlcgsglravalgmqqiatgdasiivaggmesms
maphcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafav
asqnkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegt
vtagnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkal
eragwkigdldlveaheafaaqacavnkdlgwdpsivnvnggaiaignpigasgarilnt
llfemkrrgarkglatlcigggmgvamciesl

    Sequence, based on observed residues (ATOM records): (download) 
    >2wl6A (A:)
siviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpageg
qnparqaamkagvpqeatawgmnqlcgsglravalgmqqiatgdasiivaggmesmsmap
hcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafavasq
nkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegtvta
gnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkalera
gwkigdldlveaheafaaqacavnkdlgwdpsivnvnggaiaignpigasgarilntllf
emkrrgarkglatlcigggmgvamciesl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2wl6B (B:)
stpsiviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpa
gegqnparqaamkagvpqeatawgmnqlcgsglravalgmqqiatgdasiivaggmesms
maphcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafav
asqnkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegt
vtagnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkal
eragwkigdldlveaheafaaqacavnkdlgwdpsivnvnggaiaignpigasgarilnt
llfemkrrgarkglatlcigggmgvamciesl

    Sequence, based on observed residues (ATOM records): (download) 
    >2wl6B (B:)
siviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpageg
qnparqaamkagvpqeatawgmnqlcgsglravalgmqqiatgdasiivaggmesmsmap
hcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafavasq
nkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegtvta
gnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkalera
gwkigdldlveaheafaaqacavnkdlgwdpsivnvnggaiaignpigasgarilntllf
emkrrgarkglatlcigggmgvamciesl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2wl6C (C:)
stpsiviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpa
gegqnparqaamkagvpqeatawgmnqlcgsglravalgmqqiatgdasiivaggmesms
maphcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafav
asqnkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegt
vtagnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkal
eragwkigdldlveaheafaaqacavnkdlgwdpsivnvnggaiaignpigasgarilnt
llfemkrrgarkglatlcigggmgvamciesl

    Sequence, based on observed residues (ATOM records): (download) 
    >2wl6C (C:)
siviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpageg
qnparqaamkagvpqeatawgmnqlcgsglravalgmqqiatgdasiivaggmesmsmap
hcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafavasq
nkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegtvta
gnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkalera
gwkigdldlveaheafaaqacavnkdlgwdpsivnvnggaiaignpigasgarilntllf
emkrrgarkglatlcigggmgvamciesl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2wl6D (D:)
stpsiviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpa
gegqnparqaamkagvpqeatawgmnqlcgsglravalgmqqiatgdasiivaggmesms
maphcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafav
asqnkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegt
vtagnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkal
eragwkigdldlveaheafaaqacavnkdlgwdpsivnvnggaiaignpigasgarilnt
llfemkrrgarkglatlcigggmgvamciesl

    Sequence, based on observed residues (ATOM records): (download) 
    >2wl6D (D:)
siviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpageg
qnparqaamkagvpqeatawgmnqlcgsglravalgmqqiatgdasiivaggmesmsmap
hcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafavasq
nkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegtvta
gnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkalera
gwkigdldlveaheafaaqacavnkdlgwdpsivnvnggaiaignpigasgarilntllf
emkrrgarkglatlcigggmgvamciesl