PDB entry 2wkm

View 2wkm on RCSB PDB site
Description: x-ray structure of pha-00665752 bound to the kinase domain of c-met
Class: transferase
Keywords: hepatocyte growth factor receptor, c-met, kinase, inhibitor, transferase
Deposited on 2009-06-15, released 2010-08-25
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-09-28, with a file datestamp of 2011-09-23.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.2183
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hepatocyte growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2wkma_
  • Heterogens: PFY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wkmA (A:)
mvhidlsalnpelvqavqhvvigpsslivhfnevigrghfgcvyhgtlldndgkkihcav
kslnritdigevsqfltegiimkdfshpnvlsllgiclrsegsplvvlpymkhgdlrnfi
rnethnptvkdligfglqvakgmkylaskkfvhrdlaarncmldekftvkvadfglardm
ydkeyysvhnktgaklpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvnt
fditvyllqgrrllqpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfigehh
hhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2wkmA (A:)
npelvqavqhvvigpsslivhfnevigrghfgcvyhgtlldndgkkihcavkslnritdi
gevsqfltegiimkdfshpnvlsllgiclrsegsplvvlpymkhgdlrnfirnethnptv
kdligfglqvakgmkylaskkfvhrdlaarncmldekftvkvadfglardmydkeyysvh
nktgaklpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvntfditvyllq
grrllqpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfi